A 41-year-old man with a history of gout presented with an enlarging eyelid growth. Clinical examination revealed a mildly indurated nodule at the lateral canthus. Following resection, histopathological examination revealed needle-shaped, crystalline material surrounded by multinucleated giant cells, findings consistent with gouty tophus. This represents just the sixth case of gouty tophus of the eyelid reported in the literature.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5116339 | PMC |
| http://dx.doi.org/10.1155/2016/9786810 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Quality of life and clinical gout assessments during pegloticase with and without methotrexate co-therapy: MIRROR randomized controlled trial exploratory findings.
Rheumatol Adv Pract
November 2024
Rheumatology, Western Washington Arthritis Clinic, Bothell, WA, USA.
Article Synopsis
- Pegloticase effectively lowers serum urate levels in patients with uncontrolled gout, but its use is limited by the development of anti-drug antibodies.
- Co-administration of methotrexate (MTX) was found to enhance the urate-lowering response and reduce the risk of infusion reactions, benefiting patients with limited treatment options.
- In a study involving 100 patients, those receiving pegloticase and MTX showed greater improvements in gout response rates compared to those receiving pegloticase and a placebo after 52 weeks of treatment.
Ultrasonographic Evaluation of Urate Crystal Deposition in Tendons With Gout Patients.
Int J Rheum Dis
December 2024
Department of Ultrasound, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, China.
Objective: To use ultrasound technology to assess the deposition of urate crystals in the common lower limb tendons of patients with gout, providing additional imaging information for the management of these patients.
Methods: High-frequency ultrasound was retrospectively used to evaluate urate crystal deposition in common lower limb tendons-quadriceps, patellar, and Achilles-in patients with gouty arthritis. Comparative statistical analysis was conducted among asymptomatic hyperuricemia patients and healthy individuals during the same period.
Eyelid gouty tophus.
Eye (Lond)
October 2024
Joint Shantou International Eye Center (JSIEC) of Shantou University and the Chinese University of Hong Kong, Shantou University, Shantou, 515041, China.
Multiple gouty tophi in a six-year-old.
Ghana Med J
September 2024
General Surgery Unit, Department of Surgery, Bowen University Teaching Hospital, Iwo, Osun State, Nigeria.
Article Synopsis
- - Gouty tophus is a rare condition in children, with very few noted cases in recent literature, highlighting its unusual presentation.
- - The case involves a 6-year-old girl who had swelling in her lower limbs for two years, causing difficulty in walking; biopsies revealed the presence of gouty tophus, leading to treatment with febuxostat and significant improvement in her condition.
- - It's crucial for healthcare providers to recognize potential gouty tophus in young children with subcutaneous swellings to enable timely treatment and prevent complications.
From Patents to Progress: Unraveling Gout's Journey Through Clinical Trials and Advancements.
Rev Recent Clin Trials
October 2024
Department of Pharmaceutics, Lovely Professional University, Phagwara, Punjab, 144001, India.
Article Synopsis
- Gout is an inflammatory arthritis linked to high levels of uric acid in the blood, leading to crystal formation and inflammation.
- The review highlights the rising prevalence of gout, its impact on public health, and various management strategies, including medications, dietary modifications, and lifestyle changes.
- Recent research explores innovative treatments like nanoparticles and new drugs, as well as advanced diagnostics for better detection and management of gout.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!