Purpose: The purpose of this work is to develop and evaluate a single framework for the use of Cartesian and non-Cartesian segmented trajectories for rapid and robust simultaneous multislice (SMS) diffusion weighted imaging (DWI) at 3 Telsa (T).
Methods: A generalized SMS approach with intrinsic phase navigation using Multiplexed Sensitivity Encoding (MUSE) was developed. Segmented blipped-controlled aliasing in parallel imaging echo planar imaging (EPI) and z-gradient modulated spiral trajectories were examined using SMS DWI scans at 3T with a 32-channel head coil.
Results: The generalized SMS MUSE reconstruction framework was successful in significantly reducing artifacts for all trajectories. A DWI brain volume with a 67.5-mm height, 1.5-mm isotropic resolution, and 90 diffusion weightings was obtained in a scan time of 6 minutes.
Conclusion: The MUSE technique can be generalized to allow for reconstruction of both Cartesian and non-Cartesian segmented trajectories. Magn Reson Med 78:1476-1481, 2017. © 2016 International Society for Magnetic Resonance in Medicine.
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