A new method of displaying SPECT (single photon emission tomography) thallium-201 images is described in which cardiac activity is constructed as a cylindrical map. Exercise thallium-201 scintigrams from 52 patients with known or suspected coronary artery disease are analysed by this technique and a simplified severity score devised.
Download full-text PDF |
Source |
---|
Talanta
January 2025
Pharmaceutical Chemistry Research Laboratory I, Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, 221005, India. Electronic address:
The cholinergic deficits and amyloid beta (Aβ) aggregation are the mainstream simultaneously observed pathologies during the progression of Alzheimer's disease (AD). Deposited Aβ plaques are considered to be the primary pathological hallmarks of AD and are contemplated as promising diagnostic biomarker. Herein, a series of novel theranostic agents were designed, synthesised and evaluated against cholinesterase (ChEs) enzymes and detection of Aβ species, which are major targets for development of therapeutics for AD.
View Article and Find Full Text PDFJ Am Chem Soc
January 2025
Department of Chemistry, University of Florida, Gainesville, Florida 32611, United States.
Precisely controlling quantum states is relevant in next-generation quantum computing, encryption, and sensing. Chiral organic chromophores host unique light-matter interactions, which allow them to manipulate the quantized circular polarization of photons. Axially chiral organic scaffolds, such as helicenes or twisted acenes, are powerful motifs in chiral light manipulation.
View Article and Find Full Text PDFBiomed Opt Express
January 2025
Warsaw University of Technology, Institute of Micromechanics and Photonics, 8 Sw. A. Boboli St., 02-525 Warsaw, Poland.
A fair comparison of multiple live cell cultures requires examining them under identical environmental conditions, which can only be done accurately if all cells are prepared simultaneously and studied at the same time and place. This contribution introduces a multiplexed lensless digital holographic microscopy system (MLS), enabling synchronous, label-free, quantitative observation of multiple live cell cultures with single-cell precision. The innovation of this setup lies in its ability to robustly compare the behaviour, i.
View Article and Find Full Text PDFAcc Chem Res
January 2025
Mineralogical Society of Antwerp, Boterlaarbaan 225, 2100 Deurne, Belgium.
ConspectusWhile photochromic natural sodalites, an aluminosilicate mineral, were originally considered as curiosities, articles published in the past ten years have radically changed this perspective. It has been proven that their artificial synthesis was easy and allowed compositional tuning. Combined with simulations, it has been shown that a wide range of photochromic properties were achievable for synthetic sodalites (color, activation energy, reversibility, etc.
View Article and Find Full Text PDFWe report lasing action in a femtosecond-laser-inscribed waveguide in thulium-doped barium-gallium-germanium oxide (BGG) glass. A laser cavity was assembled with this waveguide that provided a single-mode output of 62 mW when pumped at 1.6 µm.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!