The real-life effectiveness of psychosocial therapies on social autonomy in schizophrenia patients: Results from a nationwide cohort study in France.

Psychiatry Res

CESP, Paris-Sud University,  Paris-Saclay University, INSERM, 16 avenue Paul Vaillant-Couturier, 94805 Villejuif, France; LASER Analytica, 10 place de Catalogne, 75014 Paris, France. Electronic address:

Published: January 2017

AI Article Synopsis

  • The study aimed to analyze how psychosocial therapies are prescribed and evaluate the effects of psychoeducation on schizophrenia patients' symptoms and social autonomy.
  • Using data from a nationwide French study with over 5,900 patients, researchers compared those who started psychosocial therapy early on to those who did not.
  • Results showed that while both groups had similar symptom severity after 6 months, those who participated in psychoeducation showed significantly greater improvement in social autonomy.

Article Abstract

The objectives of the present study were to describe the prescribing patterns for psychosocial therapies in routine clinical practice and to assess the impact of psychoeducation on symptoms and social autonomy of patients with schizophrenia. We used data from the nationwide French ESPASS observational cohort study including 5967 patients with schizophrenia, which provided data on exposure to psychosocial therapies from 4961 (83%) participants. Patients who initiated psychosocial therapy within the first 3 months of study onset (n=143) were compared to patients not subject to psychosocial therapy throughout follow up (n=4268), using parametric tests. Symptom severity and social autonomy at 6 months from baseline were compared between patients undergoing psychoeducation (n=117) and patients not subject to psychosocial therapy, matched (1:1) on propensity scores. Patients who initiated psychosocial therapy were significantly younger, more severely ill and used less often antipsychotic drugs than patients in the reference group. At 6 months, patients who initiated psychoeducation and their matched referents did not differ significantly in terms of symptom severity, but their level of improvement in social autonomy was significantly greater (p=0.005). In routine clinical practice, psychoeducation in addition to antipsychotic drugs provides some benefit among schizophrenia patients, particularly in terms of social autonomy.

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http://dx.doi.org/10.1016/j.psychres.2016.10.048DOI Listing

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