Graphitic carbon nitride (g-CN) is applied as a support of the Pd catalyst for direct HCOOH synthesis by CO hydrogenation under neutral conditions. The high CO affinity of g-CN is responsible for the enhanced catalytic activity and stability relative to the inert support such as a carbon nanotube.
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http://dx.doi.org/10.1039/c6cc07401d | DOI Listing |
Front Immunol
January 2025
Division of Urology, Department of Surgery, Endeavor Health (formerly NorthShore University HealthSystem), Evanston, IL, United States.
Introduction: Macrophages exhibit marked phenotypic heterogeneity within and across disease states, with lipid metabolic reprogramming contributing to macrophage activation and heterogeneity. Chronic inflammation has been observed in human benign prostatic hyperplasia (BPH) tissues, however macrophage activation states and their contributions to this hyperplastic disease have not been defined. We postulated that a shift in macrophage phenotypes with increasing prostate size could involve metabolic alterations resulting in prostatic epithelial or stromal hyperplasia.
View Article and Find Full Text PDFInt J Pept Res Ther
January 2025
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, United States 46202.
Purpose: Heterozygous mutations in the insulin gene can give rise to a monogenic diabetes syndrome due to toxic misfolding of the variant proinsulin in the endoplasmic reticulum (ER) of pancreatic β-cells. Clinical mutations are widely distributed in the sequence (86 amino acids). Misfolding induces chronic ER stress and interferes in with wildtype biosynthesis and secretion.
View Article and Find Full Text PDFSci Rep
January 2025
Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing, 100081, China.
Loess is extensively developed on both sides of the Longwu River, a tributary of the Yellow River, Tongren County, Qinghai Province. The engineering geological characteristics are complex, and landslide disasters are highly developed. Based on field geological surveys and physical property analysis of the loess in this area, this study analyzes the influence of water content, consolidation pressure, and soil disturbance on the dynamic characteristics of loess using GDS dynamic triaxial tests.
View Article and Find Full Text PDFJMIR Form Res
January 2025
Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA, United States.
Background: Interstitial cystitis/bladder pain syndrome (IC/BPS) is a multifactorial, chronic syndrome involving urinary frequency, urgency, and bladder discomfort. These IC/BPS symptoms can significantly impact individuals' quality of life, affecting their mental, physical, sexual, and financial well-being. Individuals sometimes rely on peer-to-peer support to understand the disease and find methods of alleviating symptoms.
View Article and Find Full Text PDFMicrob Pathog
January 2025
Department of Laboratory Medicine, Suzhou Mental Health Center, the Affiliated Guangji Hospital of Soochow University, Suzhou215137, Jiangsu, China.
Enterovirus 71 (EV-71) is a major pathogenic factor that causes hand, foot, and mouth disease in young children and infants. Given the limited treatments for EV-71 infection, discovering new host factors and understanding the mechanisms involved will aid in combating this viral infection. Neutral sphingomyelinase-2 (nSMase-2, encoded by SMPD3) is a crucial cellular cofactor in viral infection.
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