AI Article Synopsis
- A systematic review was conducted to compare the effectiveness and safety of open versus laparoscopic surgeries for adrenal tumors, analyzing clinical trials from 1999 to 2016.
- The meta-analysis included data from 2340 patients and found laparoscopic surgery to be beneficial in terms of quicker recovery, shorter hospital stays, fewer complications, and less blood loss compared to open surgery.
- However, there was no significant difference in the cost of surgery between the two approaches, leading to the conclusion that laparoscopic surgery is generally more advantageous.
Article Abstract
Objective: To systematically review the effectiveness and safety of open and laparoscopic surgeries for treatment of adrenal tumors.
Methods: The online databases including CNKI, PUBMED, SinoMed, EBSCO, Springerlink, WanFang Data, and VIP were searched for clinical trials published from 1999 to 2016. A meta-analysis was performed using RevMan 5.2 software.
Results: A total of 2340 patients in 25 trials were included. The results of meta-analysis showed that laparoscopic surgery was better than open surgery in terms of intestinal function recovery time (OR=-0.96, 95%CI [-1.22, -0.70] P<0.000 01), hospitalization time (OR=-3.48, 95%CI [-4.13, -2.78], P<0.000 01), complications (OR=0.22, 95%CI [0.14, 0.35], P<0.0001), and volume of blood loss (OR=-104.77, 95%CI [-138.95, -70.60], P<0.000 01). There was no significant difference in the surgery cost between open and laparoscopic surgeries.
Conclusion: Laparoscopic surgery is superior to open surgery for treatment of adrenal tumors for shorter intestinal function recovery time, surgery duration, and hospitalization time and less complications and blood loss.
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