Electrooxidation and Determination of Dopamine Using a Nafion®-Cobalt Hexacyanoferrate Film Modified Electrode.

Sensors (Basel)

UNESP - Instituto de Química- Departamento de Química Analítica, 14800-900 - Araraquara, SP, Brazil.

Published: March 2008

The electrocatalysis of dopamine has been studied using a cobalt hexacyanoferrate film (CoHCFe)-modified glassy carbon electrode. Using a rotating disk CoHCFe-modified electrode, the reaction rate constant for dopamine was found to be 3.5 × 105 cm³ mol s at a concentration of 5.0 × 10 mol L. When a Nafion film is applied to the CoHCFe-modified electrode surface a high selectivity for the determination of dopamine over ascorbic acid was obtained. The analytical curve for dopamine presented linear dependence over the concentration range from 1.2 × 10 to 5.0 × 10 mol L with a slope of 23.5 mA mol L and a linear correlation coefficient of 0.999. The detection limit of this method was 8.9 × 10-6 mol L and the relative standard deviation for five measurements of 2.5 × 10-4 mol L dopamine was 0.58%.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663035PMC
http://dx.doi.org/10.3390/s8031950DOI Listing

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