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Components of Empathy in Children: Factor Structure of the Empathy Quotient for Children (EQ-C).
J Autism Dev Disord
January 2025
School of Psychology, Pevensey Building, University of Sussex, Brighton, BN1 9QJ, UK.
Empathy is multifaceted, involving sharing and understanding the emotional and mental states of others. This study investigated the factor structure of the English-language version of the Empathy Quotient for Children (EQ-C; Auyeung et al., 2009), an empathy measure previously well-validated only as a global scale.
View Article and Find Full Text PDFThrombin generation after prothrombin complex concentrate or plasma transfusion during cardiac surgery.
J Thromb Thrombolysis
December 2024
Department of Anesthesiology and Perioperative Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Thrombin generation (TG) is reduced after cardiac surgery using cardiopulmonary bypass (CPB), contributing to coagulopathy and bleeding. Plasma transfusion or four-factor prothrombin complex concentrate (PCC) are commonly used to treat coagulopathic bleeding after CPB without knowledge of how each may restore TG. To determine the effect of PCC infusion on restoration of thrombin generation compared with plasma transfusion, we performed a laboratory-based secondary analysis of a randomized, controlled trial of adult patients undergoing cardiac surgery to assess efficacy and safety of 4 F-PCC versus plasma for treatment of perioperative coagulopathic bleeding after CPB.
View Article and Find Full Text PDFCorrespondence on 'Four-factor prothrombin complex concentrate versus andexanet alfa for the reversal of traumatic brain injuries' by Sadek .
Emerg Med J
November 2024
Inpatient Pharmacy, Trinity Health Ann Arbor, Ann Arbor, Michigan, USA.
Correspondence on 'Four-factor prothrombin complex concentrate versus andexanet alfa for the reversal of traumatic brain injuries' by Sadek .
Emerg Med J
November 2024
AstraZeneca, Wilmington, Delaware, USA.
Objectives: Virally suppressed people with HIV (VS-PWH) show heterogeneity in patterns of cognitive dysfunction. To better understand the relationship between the neuroimmune response and cognition, we used PET to image the translocator protein 18 kDa (TSPO). The study examined HIV-serostatus differences in TSPO as well as associations between regional TSPO and select cognitive processes defined using the Research Domain Criteria (RDoC) framework.
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