Aging Hematopoietic Stem Cells Make Their History.

Dev Cell

Howard Hughes Medical Institute, Stem Cell Program and Division of Pediatric Hematology/Oncology, Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address:

Published: November 2016

A major hallmark of aging is a decline in tissue regeneration. In a recent issue of Cell, Bernitz and colleagues (2016) determine the divisional history of hematopoietic stem cells (HSCs) to be a key player of regenerative potential in the aging mouse.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518776PMC
http://dx.doi.org/10.1016/j.devcel.2016.11.005DOI Listing

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