Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jgar.2013.06.001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Antimicrobial resistance profiles of and associated risk factors for nosocomial infection among patients at two tertiary healthcare facilities in Lusaka and Copperbelt Provinces, Zambia.
JAC Antimicrob Resist
October 2024
Department of Disease Control, School of Veterinary Medicine, University of Zambia, Lusaka, Zambia.
Background: Antimicrobial resistance (AMR) of pathogens such as is among the top 10 threats to global health. However, clinical and molecular data are scarce in Zambia. We, therefore, evaluated the AMR profiles of nosocomial infections (NIs).
View Article and Find Full Text PDFPlasmid genomic epidemiology of carbapenem-hydrolysing class D β-lactamase (CDHL)-producing in Canada, 2010-2021.
Microb Genom
June 2024
National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Carbapenems are last-resort antibiotics for treatment of infections caused by multidrug-resistant , but carbapenem resistance is a rising global threat due to the acquisition of carbapenemase genes. Oxacillinase-48 ( )-type carbapenemases are increasing in abundance in Canada and elsewhere; these genes are frequently found on mobile genetic elements and are associated with specific transposons. This means that alongside clonal dissemination, genes can spread through plasmid-mediated horizontal gene transfer.
View Article and Find Full Text PDFPrevalence and characteristics of ertapenem-mono-resistant isolates among carbapenem-resistant Enterobacterales in China.
Emerg Microbes Infect
December 2024
Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
Carbapenem-resistant Enterobacterales (CRE), specifically those resistant to only ertapenem among carbapenems (ETP-mono-resistant), are increasingly reported, while the optimal therapy options remain uncertain. To investigate the prevalence and characteristics of ETP-mono-resistant CRE, CRE strains were systematically collected from 102 hospitals across China between 2018 and 2021. A 1:1 randomized matching study was conducted with ETP-mono-resistant strains to meropenem- and/or imipenem-resistant (MEM/IPM-resistant) strains.
View Article and Find Full Text PDFNanopore sequencing elucidates development of meropenem resistance by insertion of a mobile genetic element in the porin gene in .
Access Microbiol
February 2024
Department of Medical Microbiology and Infection Prevention, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands.
An ESBL-producing isolate recovered from a patient undergoing long-term treatment developed resistance to meropenem without acquiring carbapenem-hydrolysing enzymes. We performed Nanopore and Illumina sequencing and subsequent full hybrid genome assembly of this isolate and the meropenem-susceptible isolate recovered almost 8 weeks prior. Whole genome MLST patterns did not differ between isolates.
View Article and Find Full Text PDFenzyme SME-2 isolated from sputum in New Zealand.
JAC Antimicrob Resist
December 2023
Canterbury Health Laboratories/Te Waipounamu/Waitaha Canterbury, Te Whatu Ora-Health New Zealand, Christchurch, New Zealand.
Introduction: The enzymes (SMEs) are chromosomally encoded Ambler Class A carbapenem-hydrolysing β-lactamases, which distinctively express resistance to carbapenems while remaining susceptible to extended-spectrum cephalosporins. Global reports of SMEs are infrequent. Here we describe the isolation of an SME-2-producing from the sputum of a patient who was hospitalized at Christchurch Hospital, New Zealand.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!