Chirality sensing and discrimination of lysine derivatives in water with a dyn[4]arene.

Chem Commun (Camb)

Institut de Chimie et Biochimie Moléculaires et Supramoléculaires, UMR 5246 CNRS - Université Claude Bernard Lyon 1 - CPE Lyon - INSA, 43 Boulevard du 11 Novembre 1918, 69622 Villeurbanne cedex, France.

Published: December 2016

The asymmetric deformation of a dyn[4]arene upon the binding of various lysine derivatives leads to distinct induced circular dichroism outputs in buffered water, which can be exploited not only for the determination of their enantiomeric excesses, but also for their classification by linear discriminant analysis.

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Source
http://dx.doi.org/10.1039/c6cc07713gDOI Listing

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