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Flegel's Disease A Very Rare Skin Disease: A Case Report of Mother and Daughter in a Family.
Mymensingh Med J
January 2025
Dr Md Mostaque Mahmud, Associate Professor, Department of Dermatology & Venereology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh; E-mail:
Flegel's disease (FD) or hyperkeratosis lenticularis perstans (HLP) is an extremely exceptional skin disease typified by hyper-keratotic papules usually found on the lower extremities. Only the histopathological study is the confirmatory test for diagnosis this disease. The treatment of Flegel's disease is not yet settled as a standard one.
View Article and Find Full Text PDFCase report: Abrocitinib: a potential therapeutic option for lichen amyloidosis associated with atopic dermatitis.
Front Immunol
November 2024
School of Medicine, Tongji University, Shanghai, China.
Lichen amyloidosis (LA) is a predominant type of primary cutaneous amyloidosis that is characterized by persistent and intense skin itching. Although multiple therapeutics strategies are available for its treatment, there is no standard treatment so far. Abrocitinib, an oral small-molecule Janus kinase 1 inhibitor, has been authorized for the treatment of severe atopic dermatitis (AD) and can also provide rapid relief from pruritus.
View Article and Find Full Text PDFDeep Dermal Dilemma: A Case Report on Majocchi's Granuloma After Topical Steroid Use.
Cureus
October 2024
Dermatology, Venereology, and Leprosy, Sri Ramaswamy Memorial (SRM) Medical College Hospital and Research Centre, Chennai, IND.
Article Synopsis
- Majocchi's granuloma is a dermatological condition where dermatophytes invade deeper skin layers, often triggered by trauma or excessive use of topical corticosteroids.
- A 57-year-old man experienced itchy skin lesions on his right ankle after using over-the-counter steroids, leading to the diagnosis of Majocchi's granuloma evidenced by clinical and histopathological findings.
- The patient was treated with oral terbinafine and topical luliconazole, resulting in resolution of lesions within three weeks, though he was advised to continue treatment for two months.
Clinical and Dermoscopic Patterns of Basal Cell Carcinoma and Its Mimickers in Skin of Color: A Practical Summary.
Medicina (Kaunas)
August 2024
Institute of Dermatology, Department of Medical Area, University of Udine, 33100 Udine, Italy.
Article Synopsis
- Diagnosing basal cell carcinoma (BCC) in individuals with darker skin tones (dark phototypes IV-VI) is difficult due to varied presentations and fewer identifiable clues; dermoscopy can aid in identifying BCC in these patients.
- This review provides a comparison of BCC's clinical and dermoscopic patterns in people of color to those in lighter-skinned individuals, identifying common mimickers like squamous cell carcinoma and melanoma.
- Key dermoscopic features of BCC in darker skin include blue, black, and gray dots, with arborizing vessels being the primary indicator, while unique conditions in darker skin such as dermatosis papulosa nigra are also considered in differential diagnosis.
Epidermodysplasia Verruciformis (Lewandowsky and Lutz's Dysplasia).
Skinmed
September 2024
Pathology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
A woman in her twenties, with a non-consanguineous marriage, presented to the dermatology clinic with asymptomatic lesions on her face, neck, trunk, and extremities for the past 12 years. The general physical and systemic examination was unremarkable. Cutaneous examination revealed multiple hypopigmented to a few hyperpigmented, slightly scaly tinea versicolor-like macules distributed predominantly on the neck, upper portion of the back, and distal parts of the extremities (Figures 1-5).
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