AI Article Synopsis
- * Medullary thyroid cancer is mostly sporadic but 20% is inherited, linked to syndromes like multiple endocrine neoplasia and caused by changes in the RET oncogene on chromosome 10.
- * The paper highlights a hereditary case found through genetic screening and stresses the need for early diagnosis and collaboration among various medical experts for effective treatment.
Article Abstract
Thyroid cancer is an uncommon type of cancer, accounting less than 1% of all cancers in adults, and 0.5-3% of all cancers in children. There are four different types: papillary carcinoma (80-90% of cases), follicular (5-10%), medullary (5%) and anaplastic cell (2-3%). Eighty per cent of cases of medullary thyroid cancer are sporadic, but 20% are associated with an inherited syndrome that is divided into three groups: multiple endocrine neoplasia type 1, multiple endocrine neoplasia type 2 and familial medullary thyroid carcinoma. The inherited forms are caused by a disruption in the RET oncogene, which is located in the long arm of chromosome 10. A hereditary case of medullary thyroid carcinoma is presented. It was detected because of a familial genetic study. The purpose of the paper is emphasize the importance of the early diagnosis and the intervention of multidisciplinary teams of experts.
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| http://dx.doi.org/10.5546/aap.2016.e421 | DOI Listing |
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