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Voice Meets Swallowing: A Scoping Review of Therapeutic Connections.
Am J Speech Lang Pathol
January 2025
Department of Communication Sciences and Disorders, The University of Iowa, Iowa City.
Purpose: This scoping review aimed to explore the use of volitional voice tasks in assessing swallowing-related outcomes and to evaluate their therapeutic impact on swallowing disorders, including their effects on swallowing biomechanics.
Method: This scoping review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews guidelines. A literature search was performed across multiple databases (PubMed, Web of Science, and Scopus), and additional records were identified through manual searches.
Designing lysyl hydroxylase inhibitors for oral submucous fibrosis - Insights from molecular dynamics.
Int J Biol Macromol
December 2024
Center for Biotechnology, Anna University, Chennai 600 025, India. Electronic address:
Alpha-ketoglutarate (αKG) dependent Lysyl hydroxylase (LH) is a critical enzyme in the post-translational conversion of lysine into hydroxylysine in collagen triple helix and telopeptide regions. Overexpression of LH increases collagen hydroxylation and covalent cross-linkage, causing fibrosis. Currently, no drugs are available to inhibit LH potentially.
View Article and Find Full Text PDFImpact of Intracellular Proteins on μ-Opioid Receptor Structure and Ligand Binding.
J Phys Chem B
January 2025
Department of Chemistry, Furman University, Greenville, South Carolina 29613, United States.
Chronic pain is a prevalent problem affecting approximately one out of every five adults in the U.S. The most effective way to treat chronic pain is with opioids, but they cause dangerous side effects such as tolerance, addiction, and respiratory depression, which makes them quite deadly.
View Article and Find Full Text PDFEffects of a pre-enlargement on fracture incidence of reused reciprocating instruments: A clinical study.
Braz Dent J
December 2024
Dental Specialty Center, Brazilian Military Police, Minas Gerais, Brazil.
This study assessed the impact of pre-enlarging the root canal using a size 25 K-file on the fracture incidence of three reciprocating instruments after multiple uses. After a glide path performed with a size 15 K-file, the instruments (Reciproc R25, Reciproc Blue R25, and WaveOne Gold Primary) were initially used in 936 root canals. Then, for the second and third uses (933 and 927, respectively), a pre-enlargement using a size 25 K-file at the working length was done.
View Article and Find Full Text PDFOptimizing glycemic control in type 2 diabetes: the impact of the GLIDE program's personalized digital health intervention.
Front Clin Diabetes Healthc
December 2024
Medical Affairs, Digicare Health Solutions Private Limited, Ahmedabad, India.
Background: The integration of digital health applications into type 2 diabetes mellitus (T2DM) management presents promising opportunities for optimizing glycemic control, enhancing adherence, and improving health outcomes. MyTatva's Glycemic Lifestyle Intervention in Diabetes Empowerment (GLIDE) program, which integrates dietary and exercise regimens, cognitive behavioral therapy (CBT), and Internet of Things (IoT) devices, potentiates this approach. This study aimed to evaluate the effectiveness of the GLIDE program's personalized, comprehensive approach in improving glycemic control over 90 days among T2DM patients.
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