Periocular, periorbital, and orbital pathology in liver disease.

Surv Ophthalmol

Department of Ophthalmology, University of Virginia, Charlottesville, Virginia, USA; Department of Pathology, University of Virginia, Charlottesville, Virginia, USA; Emily Couric Cancer Center, Charlottesville, Virginia, USA. Electronic address:

Published: May 2017

AI Article Synopsis

  • Hepatic pathology can have hidden connections to eye diseases, impacting areas around the eyes like the eyelids and orbits.
  • The review covers different eye-related issues linked to liver disorders, including jaundice, hepatitis effects, and specific conditions like cirrhosis-related eyelid changes.
  • It also discusses more complex conditions such as Wilson disease and Alagille syndrome, along with the implications of liver transplantation on eye health.

Article Abstract

Although the connection is not often apparent, hepatic pathology may be associated with ophthalmic disease. We review the literature concerning the periocular, periorbital, and orbital manifestations of various hepatic disorders. This includes periocular or periorbital jaundice, the impact of hepatitis B and C, eyelid changes in cirrhosis, orbital mass lesions in hepatocellular carcinoma, and cutaneous vascular malformations as they are related to liver disease. The motility disorders associated with Wilson disease, the ophthalmic manifestations of Alagille syndrome, and the effects of liver transplantation are also discussed.

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Source
http://dx.doi.org/10.1016/j.survophthal.2016.11.002DOI Listing

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