Background: Reference intervals are critical for interpreting test results of a clinical laboratory. The aim of this study was to establish local reference intervals of complete blood count for healthy preschoolers in China.
Methods: Three thousand eight hundred and twenty-one blood specimens from children aged 4 months to 6 years were collected and analyzed. Complete blood counts were determined by Sysmex XT-4000i Automated Hematology Analyzer. The nonparametric 2.5th to 97.5th percentile reference ranges were calculated according to CLSI EP28-A3c guideline.
Results: Reference intervals for each blood cell parameter are determinded as follows: total WBC 4.86-12.1×10 /L for males and 4.73-12.3×10 /L for females; RBC 4.13-5.32×10 /L for males and 4.08-5.24×10 /L for females; HGB 109-145 g/L for males and 111-143 g/L for females; HCT 33.1-41.2% for males and 33.3-41.1% for females; MCH 23.5-29.7 pg for males and 24.6-30.0 pg for females; MCHC 320-365 g/L for males and 321-362 g/L for females; MCV 71.4-85.1 fL for males and 73.8-86.9 fL for females; RDW-SD 33.5-41.9 fL for males and 33.5-41.0 fL for females; RDW-CV 12.0-15.2% for males and 11.8-14.5% for females; PLT 181-475×10 /L for males and 179-456×10 /L for females; PCT 0.18-0.44% for males and 0.18-0.43% for females; MPV 8.20-11.6 fL for males and 8.20-11.5 fL for females; PDW 8.40-14.4 fL for males and 8.40-14.0 fL for females; P-LCR 12.0-36.6% for males and 11.8-35.6% for females.
Conclusions: We established local complete blood count reference intervals for apparent healthy preschoolers in China. It is necessary to establishing region-specific reference intervals of complete blood count for preschoolers.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817262 | PMC |
| http://dx.doi.org/10.1002/jcla.22095 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Age and biologic survival in patients with moderate-to-severe psoriasis: A cohort study from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR).
Br J Dermatol
January 2025
Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, The University of Manchester, Manchester, UK.
Background: The current management of psoriasis does not differentiate between young and old patients in selecting the safest and/or most effective biologic.
Objectives: To explore the effect of age at treatment initiation in response to biologics in patients with moderate-to-severe psoriasis in the UK and Eire.
Methods: Data from patients registering to the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR) from 2007-2024 on first course of Tumour Necrosis Factor (TNF), interleukin (IL) 12/13, IL-17 and IL-23 inhibitors (i) with at least 6 months' follow-up were included.
The application value of dynamic electroencephalography combined with brainstem auditory evoked potential in evaluating the degree of vascular stenosis and prognosis in patients with ischemic stroke: A retrospective analysis.
Medicine (Baltimore)
January 2025
Department of Neurology and Geriatrics, The First Affiliated Hospital of Chongqing Medical and Pharmaceutical College, Chongqing, China.
The aim was to explore the application value of dynamic electroencephalography (EEG) combined with brainstem auditory evoked potential (BAEP) in evaluating the degree of vascular stenosis and prognosis in patients with ischemic stroke (IS). This was a retrospective study using clinical data of patients with IS admitted to the First Affiliated Hospital of Chongqing Medical and Pharmaceutical College from March 2020 to March 2022. The degree of vascular stenosis and prognosis of patients were analyzed.
View Article and Find Full Text PDFUsing the PROMOTE Screener to Identify Psychosocial Risk Factors for Prenatal Substance Use.
J Addict Med
November 2024
From the National Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD (AA); Department of Obstetrics, Gynecology, and Reproductive Medicine, Renaissance School of Medicine, Stony Brook University, Stony Brook, NY (ML, HP); and Department of Psychology, Stony Brook University, Stony Brook, NY (ML, CH, HP).
Introduction: There is an urgent need to improve the identification of psychosocial vulnerabilities in clinical practice (eg, stress, unstable living conditions) and examine their contribution to prenatal substance use, especially for legal substances such as alcohol, tobacco, and recently, cannabis.
Methods: We conducted a retrospective chart review of 1842 patients who completed the PROMOTE screening instrument during their first prenatal visit to outpatient clinics of a New York State health system in 6/2019-11/2020. The PROMOTE includes 18 core items to assess psychosocial vulnerabilities including the NIDA Quick Screen assessing past year substance use.
Low Vision Rehabilitation Referral Characteristics for Patients with Neovascular Age-Related Macular Degeneration.
Healthcare (Basel)
January 2025
Division of Ophthalmology, Department of Surgery, UMass Chan-Lahey School of Medicine, Burlington, MA 01805, USA.
: Despite evidence that low vision rehabilitation (LVR) services can improve visual function in patients with neovascular age-related macular degeneration (nAMD), many patients are not directed to access these resources. This study was conducted to determine factors associated with LVR referral and to assess the visual outcomes from completed evaluations. : The study comprised a retrospective, cross-sectional analysis of patients with nAMD.
View Article and Find Full Text PDFValidation of new items for diagnosing primary hyperhidrosis and the prevalence of primary hyperhidrosis.
Clin Exp Dermatol
January 2025
Department of Clinical Medicine, Copenhagen University, Denmark; Faculty of Health and Medical Sciences Department of Clinical Medicine Blegdamsvej 3b 33.5, DK-2200 Copenhagen, Denmark.
Background: The Multi-Specialty Working Group on the Recognition, Diagnosis, and Treatment of Primary Focal Hyperhidrosis developed evidence-based consensus criteria for diagnosing primary hyperhidrosis.
Objectives: To validate new questionnaire items for self-reported classification of primary hyperhidrosis based on the consensus criteria and to estimate the prevalence of primary hyperhidrosis.
Methods: This is a cross-sectional diagnostic accuracy study.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!