Background: In our country, heart and kidney transplantation is a novel option for treatment of combined terminal heart and kidney failure. This program began in 2012 for selected patients with documented terminal heart failure and structural kidney damage with renal failure. Description of cases: Between January 1, 2012 and April 30, 2016, we made 92 orthotopic heart transplantations. In five of these cases the heart transplantation was combined with kidney transplantation.
Results: There were three male and two female patients with a mean age 25.6 ± 5.2 years (range, 17-29). The patients improved their renal function and the heart transplantation was successful with an improved quality of life. One patient died from abdominal sepsis. The other patients are doing well.
Conclusion: The combined heart-kidney transplantation is a safe and efficient procedure for patients with structural kidney and heart damage as a cause of terminal failure.
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Article Synopsis
- Dual heart-kidney transplantation (HKT) is an emerging treatment for patients with severe heart failure and kidney issues, with new guidelines from UNOS in 2023 formalizing its indications.
- Recent studies indicate that simultaneous heart-kidney transplantation (SHKT) offers better outcomes than heart transplantation alone for certain patients with renal problems, while kidney-after-heart transplantation (KAHT) serves as a safety option.
- Advances in pre- and post-transplant management, including device trials and innovative drug regimens, alongside future research in AI and biomarkers, highlight the potential of dual HKT as a vital option for patients with limited alternatives.
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