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Coordination-Induced Assembly of Intelligent Polysaccharide-Based Phototherapeutic Nanoparticles for Cancer Treatment. | LitMetric

Coordination-Induced Assembly of Intelligent Polysaccharide-Based Phototherapeutic Nanoparticles for Cancer Treatment.

Adv Healthc Mater

State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai, 200433, P. R. China.

Published: December 2016

AI Article Synopsis

  • Researchers developed smart nanoparticles made from polysaccharides that target cancer cells using light.
  • When exposed to a near-infrared laser, these nanoparticles create reactive oxygen species and heat that help destroy tumors.
  • They also offer a way to visually track tumor conditions through fluorescence, enhancing their potential as a dual therapy and diagnostic tool for cancer treatment.

Article Abstract

Smart polysaccharide-based anticancer phototherapeutic nanoparticles are prepared via a coordination-induced assembly process. Upon irradiated with a near infrared laser, the nanoparticles are not only able to simultaneously generate reactive oxygen species and hyperthermia that ablate tumors, but also possess tumor microenvironment-responsive off/on near infrared fluorescence and enhancement in photothermal effect, making them promising theranostic platform of cancer.

Download full-text PDF

Source
http://dx.doi.org/10.1002/adhm.201600877DOI Listing

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