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The biodiversity of freshwater fishes is extensive in Mexico; however, knowledge of their associated myxozoan parasites is limited. This study aimed to recognize myxozoan parasites in the endemic fish Mayaheros urophthalmus. Two new species, Myxobolusmayarum n.
View Article and Find Full Text PDFDigital and Tunable Genetically Encoded Tension Sensors Based on Engineered Coiled-Coils.
Angew Chem Int Ed Engl
January 2025
Emory University, Chemistry, 1515 Dickey Dr., 30322, Atlanta, UNITED STATES OF AMERICA.
Genetically encoded tension sensors (GETSs) allow for quantifying forces experienced by intracellular proteins involved in mechanotransduction. The vast majority of GETSs are comprised of a FRET pair flanking an elastic "spring-like" domain that gradually extends in response to force. Because of ensemble averaging, the FRET signal generated by such analog sensors conceals forces that deviate from the average, and hence it is unknown if a subset of proteins experience greater magnitudes of force.
View Article and Find Full Text PDFEndo 180 participates in collagen remodeling of the periodontal ligament during orthodontic tooth movement.
BMC Oral Health
December 2024
Department of Orthodontics, Central Laboratory, Hospital for Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Peking University School, 22th Zhongguancun South Ave, Beijing, 100081, China.
Background: Orthodontic tooth movement (OTM) relies on the remodeling of periodontal tissues, including the periodontal ligament (PDL) and alveolar bone. Collagen remodeling plays a crucial role during this process, allowing for the necessary changes in the PDL's structure and function. Endo180, an urokinase plasminogen activator receptor-associated protein, is a transmembrane receptor regulated collagen remodeling.
View Article and Find Full Text PDFEffect of simple shear on knotted polymer coils and globules.
J Chem Phys
December 2024
Johannes Gutenberg-Universität, Institut für Physik, Mainz, Germany.
Article Synopsis
- The study examines how Couette flow impacts knotted linear polymer chains through molecular dynamics simulations, focusing on their behavior under shear stress.
- Knotted polymers initially in a coil state tend to have their knots tighten when subjected to high shear rates, while displaying tumbling motion that causes fluctuations in knot sizes.
- Sheared knotted globular structures transform into a complex arrangement resembling a pearl necklace, where new knot types can emerge as the polymer reorganizes.
Azobenzene-Functionalized Semicrystalline Liquid Crystal Elastomer Springs for Underwater Soft Robotic Actuators.
Small
October 2024
Advanced Materials Division, Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea.
As actuated devices become smaller and more complex, there is a need for smart materials and structures that directly function as complete mechanical units without an external power supply. The strategy uses light-powered, twisted, and coiled azobenzene-functionalized semicrystalline liquid crystal elastomer (AC-LCE) springs. This twisting and coiling, which has previously been used for only thermally, electrochemically, or absorption-powered muscles, maximizes uniaxial and radial actuation.
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