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Hybrid Repair of Ascending Aortic Intramural Hematoma and Arch Ulcer in a 74-Year-Old Woman - A Case Report.

Am J Case Rep

January 2025

Department of Cardiovascular Surgery, Fujian Heart Medical Center, Union Hospital, Fujian Medical University, Fuzhou, Fujian, China.

BACKGROUND Acute intramural hematoma (IMH) of the ascending thoracic aorta and aortic arch is a life-threatening condition, particularly in elderly patients with comorbidities, due to its risk of progression and rupture. Unlike aortic dissection, IMH lacks an intimal tear, influencing both clinical presentation and treatment strategy. This report describes a 74-year-old hypertensive woman with type A IMH and a penetrating atherosclerotic ulcer (PAU), managed with a hybrid surgical approach that combines external Dacron wrapping of the ascending aorta and endovascular stenting of the aortic arch with in-situ fenestration of the supra-aortic arteries.

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Advanced Imaging Techniques for Atherosclerosis and Cardiovascular Calcification in Animal Models.

J Cardiovasc Dev Dis

December 2024

Department of Medicine, University of California, 650 Charles E Young Dr. S, Center for Health Sciences, Room A2-237, Los Angeles, CA 90095, USA.

The detection and assessment of atherosclerosis and cardiovascular calcification can inform risk stratification and therapies to reduce cardiovascular morbidity and mortality. In this review, we provide an overview of current and emerging imaging techniques for assessing atherosclerosis and cardiovascular calcification in animal models. Traditional imaging modalities, such as computed tomography (CT) and magnetic resonance imaging (MRI), offer non-invasive approaches of visualizing atherosclerotic calcification in vivo; integration of these techniques with positron emission tomography (PET) imaging adds molecular imaging capabilities, such as detection of metabolically active microcalcifications with F-sodium fluoride.

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Recent Advances in Micro/Nanomotor for the Therapy and Diagnosis of Atherosclerosis.

ACS Appl Mater Interfaces

December 2024

Department of Laboratory Medicine, Liuzhou Key Laboratory of Precision Medicine for Viral Diseases, Guangxi Health Commission Key Laboratory of Clinical Biotechnology (Liuzhou People's Hospital), Liuzhou People's Hospital, Liuzhou 545006, China.

Article Synopsis
  • - Atherosclerotic cardiovascular disease is a major global health issue leading to high rates of death and disability, with traditional treatments often harming other body parts.
  • - Micro/nanomotors are tiny, self-propelled devices that can navigate the bloodstream, targeting problematic areas like atherosclerotic plaques and improving treatment effectiveness.
  • - This review examines recent advances in micro/nanomotor technology for treating atherosclerotic disease, their potential in imaging plaques, and the need for personalized treatment approaches that consider individual patient factors.
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TIPS, a Trick for Transcaval TEVAR Access.

J Endovasc Ther

November 2024

Department of Interventional Radiology, University Hospital Leuven, Leuven, Belgium.

Purpose: We described an alternative access for thoracic endovascular aortic repair (TEVAR) deployment using a transjugular intrahepatic portosystemic shunt (TIPS) needle for gaining transcaval access to the abdominal aorta.

Case Report: A 63-year-old man presented with a penetrating atherosclerotic ulcer in the descending aorta. Traditional transfemoral and transaxillary access were not possible.

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An In Vitro Study of 355-nm Laser Ablation of Atherosclerotic Lesions Model.

J Biophotonics

January 2025

Institute of Laser and Opto-Electronics, The Key Laboratory of Opto-Electronics Information Technology (Ministry of Education), School of Precision Instrument and Opto-Electronics Engineering, Tianjin University, Tianjin, China.

A study of 355 nm laser with high pulse energy across various types of atherosclerotic lesion models is presented. The 355 nm laser pulses (10 ns) are delivered via a single fiber (600 μm diameter), and the ablation of calcified tissue, lipid tissue, and thrombus-like tissue are studied under varied laser fluence (40-70 mJ/mm) and repetition rate (5-30 Hz). The contact and noncontact ablation processes of chicken tibia samples (calcified tissue) are compared at 60 mJ/mm and 30 Hz, and the size of ablation particles is in the range of 0.

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