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| http://dx.doi.org/10.1371/journal.pntd.0005000 | DOI Listing |
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Utilising uniportal video-assisted thoracoscopic surgery for pericardial window: A 12-year single-centre experience in the diagnosis and treatment of pericardial effusion.
J Minim Access Surg
January 2025
Department of Thoracic Surgery, Faculty of Medicine, Atilim University, Ankara, Turkey.
Introduction: Uniportal video-assisted thoracoscopic surgery (Uni-VATS) is an effective minimally invasive technique for pericardial drainage, biopsy and window creation in cases of pericardial effusion (PE).
Patients And Methods: This retrospective study evaluated 73 patients with PE who underwent pericardial window procedures between 2012 and 2024. Intraoperative and post-operative data related to Uni-VATS were assessed.
A novel framework for increasing research transparency: Exploring the connection between diversity and innovation.
PLoS One
January 2025
Department of Agricultural Economics, Oklahoma State University, Stillwater, Oklahoma, United States of America.
A split sample/dual method research protocol is demonstrated to increase transparency while reducing the probability of false discovery. We apply the protocol to examine whether diversity in ownership teams increases or decreases the likelihood of a firm reporting a novel innovation using data from the 2018 United States Census Bureau's Annual Business Survey. Transparency is increased in three ways: 1) all specification testing and identifying potentially productive models is done in an exploratory subsample that 2) preserves the validity of hypothesis test statistics from de novo estimation in the holdout confirmatory sample with 3) all findings publicly documented in an earlier registered report and in this journal publication.
View Article and Find Full Text PDFDetermination of production capacity for open-pit coal mines under uncertainty: A model based on economies of scale.
PLoS One
January 2025
College of Mining, Liaoning Technical University, Fuxin, Liaoning Province, People's Republic of China.
The determination of optimal production capacity for open-pit mines is influenced by various economic and technical factors and is highly susceptible to uncertainties. To effectively address the impact of uncertainty on capacity planning, this study develops a production capacity planning model for open-pit coal mines, based on the theory of economies of scale and incorporating multiple uncertainty constraints. A novel method is proposed to quantify and propagate the uncertainties of key capacity control factors, alongside a comprehensive uncertainty analysis framework for total revenue.
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Alzheimers Dement
December 2024
University of Southern California, Los Angeles, CA, USA.
Background: The value payers and policymakers traditionally place on novel treatments for Alzheimer's and other neurological diseases that cause cognitive impairment (CI) and dementia often ignores disease baseline severity. More patient-centered economic evaluations-such as those estimating "insurance value"-incorporate the fact that individuals are typically risk-averse and place high value on generous coverage of treatments in the event that they develop CI, such as severe dementia, later in life. This study aims to estimate this insurance value, accounting for risk aversion, relative to the value of the same treatment based on traditional payer cost effectiveness approaches.
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Alzheimers Dement
December 2024
Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Background: To provide a nationally representative estimate of the burden of multiple comorbidities (MCM) among community-dwelling Medicare beneficiaries with Alzheimer's disease (AD) and AD related dementias (ADRD).
Method: We analyzed national sampling data in Medicare beneficiaries aged ≥65 (n = 34,318) from the 2018-2020 Medicare Current Beneficiaries Surveys. AD/ADRD and twelve chronic comorbidities (hypercholesterolemia, hypertension, diabetes, coronary heart disease, heart failure, stroke, depression, mental disorder, chronic kidney disease, chronic obstructive pulmonary disease, arthritis, and osteoporosis) were examined.
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