AI Article Synopsis

  • Gastritis cystica profunda (GCP) is a rare, non-cancerous gastric condition marked by abnormal tissue growth and cystic changes extending deeper into the stomach layers, often linked to past gastric surgeries.
  • A case study of a young woman with ongoing upper GI symptoms highlighted the challenges in diagnosis, as initial biopsies did not reveal any tumors despite imaging showing a mass.
  • Ultimately, surgical intervention was required to both clarify the diagnosis through histopathology and alleviate her symptoms, underscoring the importance of considering GCP in cases of gastric mass lesions.

Article Abstract

Gastritis cystica profunda (GCP) is a rare, benign lesion of the stomach characterized by polypoid hyperplasia and/or ulcerated mucosal lesion and cystic dilatation of the gastric glands extending into the submucosa or muscularis propria of the stomach. Its etiology and pathogenesis are still incompletely understood. The most important factor is assumed to be a history of prior gastric surgery. We herein present a case of a young adult female with upper gastrointestinal (GI) symptoms. She underwent upper GI endoscopy twice, which revealed pyloric narrowing and intramural mass. Gastric endoscopic mucosal biopsies were performed, but no tumor was identified and her symptoms persisted. Imaging studies also revealed a mass lesion. Open laparotomy and partial gastrectomy with histopathology of the resected specimen revealed the true nature of the lesion. Surgery also improved her symptoms. GCP should be kept in the differential diagnosis of gastric mural mass lesions.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936466PMC
http://dx.doi.org/10.4103/2224-4018.154296DOI Listing

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