Objectives: Superficial soft tissue injury, such as a skin tear, is common. For such wounds, the authors introduce a novel technique that allows the physician to salvage otherwise discarded tissue as a traumatic graft to highly accelerate wound healing.
Methods: A series of 11 patients with superficial soft tissue trauma in which debrided tissues are salvaged back into the wound by means of minced expansion grafting (MEG) are followed from presentation through healing.
Results: Salvaged tissue replaced back into wounds as MEG grafts greatly accelerated epithelialization and wound closure.
Conclusions: Based on their experience with MEG, the authors introduce a new principle for the wound surgeon that no tissue should ever be discarded, but rather salvaged and placed back into the wound.
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http://dx.doi.org/10.1097/01.ASW.0000499866.27975.28 | DOI Listing |
Phys Rev Lett
December 2024
CERN, Geneva, Switzerland.
High-energy nuclear collisions create a quark-gluon plasma, whose initial condition and subsequent expansion vary from event to event, impacting the distribution of the eventwise average transverse momentum [P([p_{T}])]. Disentangling the contributions from fluctuations in the nuclear overlap size (geometrical component) and other sources at a fixed size (intrinsic component) remains a challenge. This problem is addressed by measuring the mean, variance, and skewness of P([p_{T}]) in ^{208}Pb+^{208}Pb and ^{129}Xe+^{129}Xe collisions at sqrt[s_{NN}]=5.
View Article and Find Full Text PDFMethods Mol Biol
March 2024
College of Stomatology, Chongqing Medical University, Chongqing, China.
Adipose tissue provides a valuable cell source for tissue engineering, regenerative medicine, and adipose tissue biology studies. The most widely used adipose-derived stromal/stem cells (ASCs) isolation protocol involves enzymatic digestion with collagenase. However, the yield of the method often proves to be poor if not impossible for collection of sufficient stromal vascular fraction (SVF) for expansion when the sample size is small, for instance when only newborn mice are available for cell culture.
View Article and Find Full Text PDFCurr Protoc
November 2023
ACRF Department of Cancer Biology and Therapeutics and Division of Genome Sciences and Cancer, John Curtin School of Medical Research, Australian National University, Acton, Canberra, Australia.
Mouse embryonic fibroblasts (MEFs) are primary fibroblasts purified from mouse embryos at a defined time post-fertilization. MEFs have versatile applications, including use as feeder cell layers or sources of untransformed primary cells for a variety of biological assays. MEFs are most commonly isolated between embryonic day (E)12.
View Article and Find Full Text PDFAdv Wound Care (New Rochelle)
April 2024
Applied Tissue Technologies LLC, Hingham, Massachusetts, USA.
Autologous skin transplantation is limited by donor site availability for patients with extensive burns. The objective of this study was to demonstrate the feasibility and efficacy of split-thickness skin (STS) and dermal pixel grafts (PG) in the treatment of burns. The study was divided into three arms of validation, expansion, and combination that all followed the same study design.
View Article and Find Full Text PDFPhys Rev Lett
August 2023
CERN, Geneva, Switzerland.
Jet quenching is the process of color-charged partons losing energy via interactions with quark-gluon plasma droplets created in heavy-ion collisions. The collective expansion of such droplets is well described by viscous hydrodynamics. Similar evidence of collectivity is consistently observed in smaller collision systems, including pp and p+Pb collisions.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!