Background: Loss of power has been demonstrated to have severe functional consequences to perform physical daily living tasks in old age.
Purpose: This study aimed to assess how moment and velocity were affected for each joint of the lower limbs during squat jumping for older men in comparison with young adults.
Methods: Twenty-one healthy older men (74.5 ± 4.6 years) and 22 young men (21.8 ± 2.8 years) performed maximal squat jumps. Inverse dynamics procedure was used to compute the net joint power, moment and velocity produced at the hip, knee and ankle joints.
Results And Discussion: Vertical jump height of the elderly was 64 % lower than the young adults. The maximal power of the body mass center (P ) was 57 % lower in the older population. For the instant at P , the vertical ground reaction force and the vertical velocity of the body mass center were 26 % and 35 % less in the older adults than in the young adults, respectively (p < 0.05; ES = -1.64 for vertical ground reaction force; p < 0.05; ES = -1.10). A lower value of the hip (-60 %), knee (-72 %) and ankle (-68 %) joint powers was observed in older adults. This was explained by both lower values of joint moments (-64, -57 and -61 % for the hip, knee and ankle, respectively) and angular velocities (-59, -49 and -52 % for the hip, knee and ankle, respectively).
Conclusion: This study showed a lower joint power when performing vertical jump. This smaller power resulted from both a lower moment and angular velocity produced at each joint.
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http://dx.doi.org/10.1007/s40520-016-0660-0 | DOI Listing |
Mult Scler
January 2025
Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic, Rochester, MN, USA.
Background: Spinal cord (SC) atrophy is a key imaging biomarker of progressive multiple sclerosis (MS). Progressive MS is more common in men and postmenopausal women.
Objective: Investigate the impact of sex and menopause on SC measurements in persons with MS (pwMS).
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn
January 2025
Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA.
Greater neighborhood disadvantage is associated with poorer global cognition. However, less is known about the variation in the magnitude of neighborhood effects across individual cognitive domains and whether the strength of these associations differs by individual-level factors. The current study investigated these questions in a community sample of older adults ( = 166, mean age = 72.
View Article and Find Full Text PDFInt J Equity Health
January 2025
JC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Background: South Asians living in urbanized settings are facing disproportionate cardiovascular burden largely attributable to modifiable risk factors. Given the rapid surge in South Asian population in Hong Kong, this study aims to identify and distinguish clusters of cardiovascular risk profiles among community-dwelling South Asian adults.
Methods: Between June 2022 and December 2023, 1181 South Asian adults were recruited through territory-wide outreach health assessments on lifestyle, psychological distress, obesity, clinical cardiovascular conditions, and sociodemographic factors.
Environ Pollut
January 2025
Center for Endemic Disease Control, Chinese Center for Disease Control and Prevention, Harbin Medical University, Harbin, People's Republic of China; NHC Key Laboratory of Etiology and Epidemiology(Harbin Medical University); Joint Key Laboratory of Endemic Diseases(Harbin Medical University, Guizhou Medical University, Xi'an Jiaotong University); Center for Chronic Disease Prevention and Control, Harbin Medical University, Harbin, People's Republic of China. Electronic address:
Background: Skeletal fluorosis is a chronic metabolic bone disease caused by excessive accumulation of fluoride in the bones. Previous studies have found that when the intake of tea fluoride is similar, the prevalence of skeletal fluorosis varies greatly among different ethnic groups, which may be related to different genetic backgrounds. Single nucleotide polymorphisms (SNPs) of estrogen receptor 1 (ESR1) and collagen type 1 α1 (COL1A1) were strongly associated with bone metabolism as well as bone growth and development, but their association with the risk of skeletal fluorosis has not been reported.
View Article and Find Full Text PDFStem Cell Reports
January 2025
Division of Stem Cell Medicine, Graduate School of Medicine, Kobe University, Kobe, Japan; Division of Advanced Medical Science, Graduate School of Science, Technology and Innovation, Kobe University, Kobe, Japan; Center for Human Resource Development for Regenerative Medicine, Kobe University Hospital, Kobe, Japan; Division of Signal Pathways, Biosignal Research Center, Kobe University, Kobe, Japan. Electronic address:
Late-onset hypogonadism (LOH) syndrome is characterized by age-related testosterone deficiency and negatively affects the quality of life of older men. A promising therapeutic approach for LOH syndrome is transplantation of testosterone-producing Leydig-like cells (LLCs) derived from human induced pluripotent stem cells (hiPSCs). However, previous studies have encountered obstacles, such as limited cell longevity, insufficient testosterone production, and inefficiency of differentiation.
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