Little literature exists examining differences in presentation and outcomes between monomicrobial and polymicrobial vertebral infections. Seventy-nine patients treated for vertebral osteomyelitis between 2001 and 2011 were reviewed. Patients were divided into monomicrobial and polymicrobial cohorts based on type of infection. Various characteristics were compared between the 2 groups. The 26 patients with a polymicrobial infection were older and had a higher mortality rate, lower clearance of infection, larger infection, more vertebral instability, higher erythrocyte sedimentation rate at presentation, and longer mean length of stay. There were no significant differences in Oswestry Disability Index scores at final follow-up, but there were differences in presentation and clinical outcomes between monomicrobial and polymicrobial vertebral osteomyelitis. Patients may benefit from counseling regarding their disease type and potential prognosis. [Orthopedics. 2017; 40(2):e370-e373.].
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3928/01477447-20161108-05 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Metagenomic analysis identifying a polymicrobial pulmonary infection in a non-HIV immunocompromised patient: a case report.
BMC Pulm Med
January 2025
Central Laboratory, Liaocheng People's Hospital and Liaocheng School of Clinical Medicine, Shandong First Medical University, Liaocheng, Shandong, 252000, China.
Background: Polymicrobial pulmonary infections, common in immunocompromised patients, often manifest more severe symptoms than monomicrobial infections. Clinical diagnosis delays may lead to mortality, emphasizing the importance of fast and accurate diagnosis for these patients. Metagenomic next-generation sequencing (mNGS), as an unbiased method capable of detecting all microbes, is a valuable tool to identify pathogens, particularly in cases where infections are difficult to diagnosis using conventional methods.
View Article and Find Full Text PDFMonomicrobial Gram-Negative Necrotizing Fasciitis of the Lower Extremity.
Cureus
December 2024
Internal Medicine, Baylor Scott and White Health, Fort Worth, USA.
Unlike other skin and soft tissue infections, necrotizing fasciitis (NF) is a rare and potentially life-threatening condition. It is usually caused by polymicrobial infections or monomicrobial gram-positive organisms, mainly and . Monomicrobial gram-negative () NF is a rare form of NF, primarily reported in patients with underlying comorbidities or immunocompromised states.
View Article and Find Full Text PDFEvaluation of the effect of BioFire FilmArray nested multiplex polymerase chain reaction method on rapid pathogen identification and antimicrobial stewardship in sepsis.
Rev Assoc Med Bras (1992)
December 2024
Health Sciences University, Izmir Suat Seren Chest Diseases and Surgery Training and Research Hospital, Department of Intensive Care Unit - İzmir, Turkey.
Article Synopsis
- The study evaluated the impact of the BioFire FilmArray Blood Culture Identification 2 panel on identifying pathogens and guiding antibiotic treatment in critically ill sepsis patients.
- The research was a prospective observational study involving patients in the ICU with sepsis due to bloodstream infections, comparing results from the new panel to traditional blood cultures in terms of accuracy and speed.
- Results showed high sensitivity and specificity for identifying pathogens, with the new panel providing results significantly faster, suggesting it could enhance treatment effectiveness and improve outcomes for these patients.
Utility of direct microorganism species identification and antimicrobial susceptibility tests in urine samples.
J Infect Chemother
December 2024
Clinical Laboratory, Saitama Medical University International Medical Center, Saitama, Japan; Department of Laboratory Medicine, Saitama Medical University International Medical Center, Saitama, Japan. Electronic address:
Introduction: Urinary tract infections (UTIs) are one of the most common bacterial infections and a major cause of sepsis. It is important to promptly diagnose and treat UTIs.
Method: We found that a Gram-staining score of ≥2+ could be substituted for a colony-forming unit value of ≥10,000/mL.
Blood stream infections in Stevens Johnson Syndrome and Toxic Epidermal Necrolysis: Risk factors and association with poor outcome.
Pak J Med Sci
December 2024
Muhammad Zain Mushtaq, MBBS, FCPS, MRCP. Section of Internal Medicine, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Background & Objective: Blood Stream Infections (BSI) are considered a significant cause of morbidity and mortality in patients with Stevens Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN). We aimed to identify risk factors for BSI upon admission, highlight clinical and microbiological findings and ascertain the frequency of mortality in patients with BSI in SJS/TEN.
Methods: A retrospective cross-sectional study over 12 years (2011-2022) was performed in the department of medicine at a tertiary care hospital in Pakistan.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!