This study was performed to examine the psychometric properties of a Virtual-Reality Prospective Memory Test (Hong Kong Chinese version; VRPMT-CV). The VRPMT was administered to 44 individuals with first-episode schizophrenia. The test was administered again 2 weeks later to establish test-retest reliability. The concurrent validity of the VRPMT was evaluated by examining the correlations between the VRPMT score and the score on the Chinese version of the Cambridge Prospective Memory Test (CAMPROMPT-CV). The performance of individuals with schizophrenia on the VRPMT was also compared with that of 42 healthy control subjects to examine the test's sensitivity and specificity. The intraclass correlation for test-retest reliability of the total VRPMT-CV score was 0.78 (p = .005). A significant correlation was found between the total VRPMT-CV score and the total CAMPROMPT-CV score (r = 0.90; p < .001). Comparison with the healthy control subjects revealed that the total VRPMT-CV score was a sensitive (92.9%) and specific (75%) measure of prospective memory deficits in individuals with schizophrenia. The VRPMT-CV is an assessment of prospective memory that has good construct validity, test-retest reliability, sensitivity and specificity in the context of first-episode schizophrenia.
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http://dx.doi.org/10.1080/09602011.2016.1251949 | DOI Listing |
Neurology
February 2025
School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Background And Objectives: Lipid metabolism in older adults is affected by various factors including biological aging, functional decline, reduced physiologic reserve, and nutrient intake. The dysregulation of lipid metabolism could adversely affect brain health. This study investigated the association between year-to-year intraindividual lipid variability and subsequent risk of cognitive decline and dementia in community-dwelling older adults.
View Article and Find Full Text PDFGerontologist
January 2025
Department of Psychology, Clemson University, Clemson, South Carolina, USA.
Background And Objectives: The analysis of daily memory lapses is an underutilized approach to understanding daily experiences of cognitive functioning. The present study adopts this approach, with the goals of exploring how the quality of family relationships predicts the frequency of daily memory lapses and moderates the link between daily memory lapses and daily affect.
Research Design And Methods: We used longitudinal data from the third wave of Midlife in the United States and the National Study of Daily Experiences to assess our research goals.
Hum Brain Mapp
February 2025
Research Center for Social Computing and Information Retrieval, Harbin Institute of Technology, Harbin, China.
Pattern separation and pattern completion in the hippocampus play a critical role in episodic learning and memory. However, there is limited empirical evidence supporting the role of the hippocampal circuit in these processes during complex continuous experiences. In this study, we analyzed high-resolution fMRI data from the "Forrest Gump" open-access dataset (16 participants) using a sliding-window temporal autocorrelation approach to investigate whether the canonical hippocampal circuit (DG-CA3-CA1-SUB) shows evidence consistent with the occurrence of pattern separation or pattern completion during a naturalistic audio movie task.
View Article and Find Full Text PDFBMC Psychiatry
January 2025
School of Mental Health, Bengbu Medical University, Bengbu, Anhui, 233030, China.
Background: Although impaired cognitive control is common during the acute detoxification phase of substance use disorders (SUD) and is considered a major cause of relapse, it remains unclear after prolonged methadone maintenance treatment (MMT). The aim of the present study was to elucidate cognitive control in individuals with heroin use disorder (HUD) after prolonged MMT and its association with previous relapse.
Methods: A total of 63 HUD subjects (41 subjects with previous relapse and 22 non-relapse subjects, mean MMT duration: 12.
Neurobiol Aging
January 2025
Center for Lifespan Changes in Brain and Cognition, Department of Psychology, University of Oslo, Oslo 0317, Norway; Department of Radiology and Nuclear Medicine, University of Oslo, Oslo 0317, Norway.
Lower episodic memory capability, as seen in development and aging compared with younger adulthood, may partly depend on lower brain network segregation. Here, our objective was twofold: (1) test this hypothesis using within- and between-network functional connectivity (FC) during episodic memory encoding and retrieval, in two independent samples (n = 734, age 7-82 years). (2) Assess associations with age and the ability to predict memory comparing task-general FC and memory-modulated FC.
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