Background: Traumatic brain injury (TBI) is the leading cause of disability in children and young adults and costs CAD$3 billion annually in Canada. Stakeholders have expressed the urgent need to obtain information on resource use for TBI to improve the quality and efficiency of acute care in this patient population. We aimed to assess the components and determinants of hospital and ICU LOS for TBI admissions.
Methods: We performed a retrospective multicenter cohort study on 11,199 adults admitted for TBI between 2007 and 2012 in an inclusive Canadian trauma system. Our primary outcome measure was index hospital LOS (admission to the hospital with the highest designation level). Index LOS was compared to total LOS (all consecutive admissions related to the injury). Expected LOS was calculated by matching TBI admissions to all-diagnosis hospital admissions by age, gender, and year of admission. LOS determinants were identified using multilevel linear regression.
Results: Geometric mean total LOS was 1day longer than geometric mean index LOS (12.6 versus 11.7 days). Observed index and ICU LOS were respectively 4.2days and 2.5days longer than that expected according to all-diagnosis admissions. The six most important determinants of LOS were discharge destination, severity of concomitant injuries, extracranial complications, GCS, TBI severity, and mechanical ventilation, accounting for 80% of explained variation.
Conclusions: Results of this multicenter retrospective cohort study suggest that hospital and ICU LOS for TBI admissions are 56% and 119% longer than expected according to all-diagnosis admissions, respectively. In addition, hospital LOS is underestimated when only the index visit is considered and is largely influenced by discharge destination and extracranial complications, suggesting that improvements could be achieved with better discharge planning and interventions targeting prevention of in-hospital complications. This study highlights the importance of considering TBI patients as a distinct population when allocating resources or planning quality improvement interventions.
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http://dx.doi.org/10.1016/j.injury.2016.10.042 | DOI Listing |
J Occup Environ Med
November 2024
Center for Environmental and Health Sciences, Hokkaido University, Sapporo, Japan.
Objectives: As part of the "Japan Environment and Children's Study (JECS)," a national prospective birth cohort study, we examined the association between the maternal work environment and psychological distress during pregnancy in Japan.
Methods: Employing a cross-sectional design, we analyzed data from 42,797 participants, originally collected between 2011 and 2014. Associations between the maternal work environment and psychological distress (Kessler 6) were examined using generalized estimation equation models adjusted for confounding factors.
J Occup Environ Med
November 2024
Center for Environmental and Health Sciences, Hokkaido University, Sapporo, Japan.
Objective: We examined the association between the occupations of pregnant women's partners and infant low birth weight (LBW) and preterm birth (PB).
Methods: Birth outcome data were collected from 46,540 participants enrolled in the Japan Environment and Children's Study. Participants were recruited from January 2011 to March 2014.
J Occup Environ Med
November 2024
Department of Environmental Epidemiology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.
Objective: Workers were subject to both presenteeism and workplace mistreatment during the COVID-19 pandemic. We aimed to examine their association during the pandemic in Japan.Methods: An internet-based, one-year prospective cohort study was conducted from 2020 to 2021.
View Article and Find Full Text PDFNeurology
February 2025
Department of Neurology, Washington University School of Medicine, St. Louis, MO.
Objectives: Intravenous tenecteplase (TNK) is increasingly used to treat adult patients with acute arterial ischemic stroke, but the risk profile of TNK in childhood stroke is unknown. This study aims to prospectively gather safety data regarding TNK administration in children.
Methods: Since December 2023, a monthly email survey was sent to participants recruited from the International Pediatric Stroke Study and Pediatric Neurocritical Care Research Group querying recent experience with TNK in childhood stroke.
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