Purpose: To determine the factors associated with retreatment after laser in situ keratomileusis (LASIK) for myopic eyes in the modern LASIK era.
Setting: Care-Vision Laser Centers, Tel-Aviv, Israel.
Design: Retrospective cohort study.
Methods: All cases of myopic LASIK performed between January 2005 and December 2012 were analyzed according to whether they had retreatment refractive surgery.
Result: The study evaluated 9177 right eyes in 9177 consecutive LASIK cases. The mean preoperative subjective spherical equivalent and astigmatism were -3.30 diopters (D) ± 1.53 (SD) (range -0.50 to -12.00 D) and 0.69 ± 0.94 D (range 0.00 to 6.00 D), respectively. Of the eyes, 165 (1.80%) had at least 1 retreatment. Over the course of the study, the 2-year retreatment rate decreased from 2.58% to 0.38% (P < .001). Multiple binary logistic regression analysis showed that older age (odds ratio [OR], 1.03; P = .007), higher astigmatism (OR, 1.23; P = .008), sphere (OR, 1.15; P = .026), and mean keratometric power (OR, 1.13; P = .036) significantly increased the odds for retreatment. A larger optical zone ablation (7.0 mm) significantly decreased the odds for retreatment (OR, 0.10; P = .022). Significant cutoffs associated with retreatments were age greater than 50 years, astigmatism more than 1.5 D, and sphere more than 2.0 D.
Conclusions: Older age and higher preoperative astigmatism, sphere, and corneal steepness were associated with myopic LASIK retreatment. Larger optical ablation zones might decrease retreatment rates.
Financial Disclosure: None of the authors has a financial or proprietary interest in any material or method mentioned.
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http://dx.doi.org/10.1016/j.jcrs.2016.07.032 | DOI Listing |
ACS Phys Chem Au
January 2025
Department of Medical Applied Chemistry, Chung Shan Medical University, Taichung 402, Taiwan.
Novel coumarin-triphenyliminophosphorane (TPIPP) fluorophores, synthesized via a nonhydrolytic Staudinger reaction, exhibit remarkable redox-responsive optical properties. Upon chemical and electrochemical oxidation, these compounds display a hypsochromic shift in absorption from 430 to 350 nm, accompanied by up to 11-fold fluorescence enhancement under 405 nm excitation. The fluorescence switching occurs at an electrochemical oxidation potential of approximately +2.
View Article and Find Full Text PDFAnal Chem
January 2025
School of Environmental & Chemical Engineering, Jiangsu University of Science and Technology, Changhui Rd. 666, Zhenjiang, Jiangsu 212003, China.
Early diagnosis of tumors allows effective treatment of primary cancers through localized therapeutic interventions. However, developing diagnostic tools for sensitive, simple, and early tumor (especially less than 2 mm in diameter) detection remains a challenge. Herein, we presented a biomarker-activatable nanoprobe that enabled a near-infrared (NIR) photothermally amplified signal for fluorescence imaging and urinalysis of tumor.
View Article and Find Full Text PDFPhytomedicine
January 2025
State key laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, National Chinmedomics Research Center, National TCM Key Laboratory of Serum Pharmacochemistry, Metabolomics Laboratory, Department of Pharmaceutical Analysis, Heilongjiang University of Chinese Medicine, Heping Road 24, Harbin 150040, China; Department of Nephrology, Nephrology Institute of the Chinese People's Liberation Army, National Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China. Electronic address:
Background: Huangkui capsule (HKC), a Chinese patent medicine, is clinically used for treating diabetic nephropathy. However, the core disease-specific biomarkers and targets of type 2 diabetic nephropathy (T2DN) and the therapeutic mechanism of HKC are not fully elucidated.
Purpose: This study aimed to investigate the therapeutic effects and underlying molecular mechanisms of HKC for T2DN.
Materials (Basel)
January 2025
Institute of Chemistry, St. Petersburg State University, 199034 St. Petersburg, Russia.
Deep eutectic solvents (DES) have emerged as versatile, sustainable media for the synthesis of nanomaterials due to their low toxicity, tunability, and biocompatibility. This study develops a one-step method to modify commercially available screen-printed electrodes (SPE) using laser-induced pyrolysis of DES, consisting of choline chloride and tartaric acid with dissolved nickel acetate and dispersed graphene. The electrodes were patterned using a 532 nm continuous-wave laser for the in situ formation of Ni nanoparticles decorated on graphene sheets directly on the SPE surface (Ni-G/SPE).
View Article and Find Full Text PDFMicromachines (Basel)
December 2024
Taiwan Instrument Research Institute, National Applied Research Laboratories, Hsinchu 300092, Taiwan.
The development of bionic organ-on-a-chip technology relies heavily on advancements in in situ sensors and biochip packaging. By integrating precise biological and fluid condition sensing with microfluidics and electronic components, long-term dynamic closed-loop culture systems can be achieved. This study aims to develop biocompatible heterogeneous packaging and laser surface modification techniques to enable the encapsulation of electronic components while minimizing their impact on fluid dynamics.
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