Stability of direct oral anticoagulants in whole blood and plasma from patients in steady state treatment.

Thromb Res

Department of Clinical Biochemistry, Aarhus University Hospital, Denmark; Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark. Electronic address:

Published: December 2016

Using functional haemostasis assays, we demonstrated important differences in stability of direct oral anticoagulants (DOACs) in citrated whole blood and plasma from DOAC treated patients. Laboratories and clinicians should take this into consideration and adjust clinical practices accordingly.

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http://dx.doi.org/10.1016/j.thromres.2016.10.023DOI Listing

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