We present a simple method for the multiplexed formation of droplet interface bilayers (DIBs) using a mechanically operated linear acrylic chamber array. To demonstrate the functionality of the chip design, a lipid membrane permeability assay is performed. We show that multiple, symmetric DIBs can be created and separated using this robust low-cost approach.
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http://dx.doi.org/10.1039/c6lc01011c | DOI Listing |
Langmuir
January 2025
Department of Chemistry and Biochemistry, Iona University, 715 North Avenue, New Rochelle, New York 10801, United States.
Understanding the evolution of protocells, primitive compartments that distinguish self from nonself, is crucial for exploring the origin of life. Fatty acids and monoglycerides have been proposed as key components of protocell membranes due to their ability to self-assemble into bilayers and vesicles capable of nutrient exchange. In this study, we investigate the electrophysiological properties of planar bilayers composed of monoglyceride and fatty acid mixtures, using a droplet interface bilayer system.
View Article and Find Full Text PDFLangmuir
January 2025
Shandong Key Laboratory of Oilfield Chemistry, Department of Petroleum Engineering, China University of Petroleum (East China), Qingdao 266580, China.
The oil film formed by the adhesion of crude oil to the resin-asphalt adsorption layer is difficult to peel off due to the strong oil-solid interaction, which severely limits further improvements in oil recovery. Although conventional compound oil displacement systems can effectively reduce oil-water interfacial tension, facilitate oil droplet deformation, and alleviate the Jamin effect, they are insufficient in controlling the wettability of oleophilic rock surfaces. In this paper, sodium nonylphenol polyoxyethylene ether sulfate (NPES) and sodium lauric acid ethanolamine sulfonate (HLDEA) were compounded to construct an efficient oil displacement system that simultaneously achieves wettability control of lipophilic surfaces and ultralow oil-water interfacial tension.
View Article and Find Full Text PDFJ Vasc Interv Radiol
January 2025
Department of Diagnostic and Interventional Radiology, Osaka University Graduate School of Medicine. 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Purpose: This research aimed to develop and assess a Lipiodol Pickering emulsion containing anti-Programmed cell Death Ligand 1 (PD-L1) antibodies through in vitro experiments.
Materials And Methods: The emulsion was created by combining Lipiodol with poly (lactic-co-glycolic acid) (PLGA) nanoparticles and anti-PD-L1 antibodies. Confocal laser microscopy was used to evaluate the encapsulation of the antibodies within the Pickering emulsion.
Foods
January 2025
Department of Food Science and Technology, School of Agriculture, Shiraz University, Shiraz, Iran.
Emulsifiers with antioxidant properties, such as protein/polyphenol complexes, adsorb at the oil-water interface and improve the physical and oxidative stability of emulsions. Here, 2% (/) sodium caseinate and varying concentrations of phloretin (0-10 mM) were used to stabilize oil-in-water emulsions. Control emulsions with protein alone showed poor stability with increased droplet sizes from 0.
View Article and Find Full Text PDFFoods
January 2025
Guangdong Engineering Laboratory of Biomass High-Value Utilization, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences, Guangzhou 510316, China.
Fungi polysaccharides are nutraceutical-rich compounds with bioactive properties, offering promising applications in food formulation. This study examined the non-covalent complexation of commercial polysaccharides derived from the fruiting bodies of (AA) and (GL) and soy protein isolate to enhance emulsifying properties. Complexes were examined across protein-to-polysaccharide ratios (0:1 to 1:0), pH levels (3 to 7), and heat treatment conditions.
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