Repeated experimental reinfection of two subjects indicates that infection does not promote an immune response protective against future reinfection. Our results highlight the importance of preventing reinfection after eradication, through public health initiatives, and possibly treatment of family members. They indicate difficulties for vaccine development, especially therapeutic vaccines.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093156PMC
http://dx.doi.org/10.1002/ccr3.687DOI Listing

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