Cyanobacterial Mn-catalase 'KatB': Molecular link between salinity and oxidative stress resistance.

Commun Integr Biol

Molecular Biology Division, Bhabha Atomic Research Center, Trombay, Mumbai, India; Homi Bhabha National Institute, Anushakti Nagar, Mumbai, India.

Published: August 2016

Catalases are ubiquitous enzymes that detoxify HO in virtually all organisms exposed to oxygen. The filamentous, nitrogen-fixing cyanobacterium, PCC 7120, shows the presence of 2 genes ( and ) that encode Mn-catalases. We have recently shown that pre-treatment of with NaCl causes substantial induction of the KatB protein, which consequently leads to increased oxidative stress resistance in that cyanobacterium. Interestingly, when compared to the wild-type, the mutant shows decreased growth and impaired photosynthetic activity in the presence of NaCl. Furthermore, the NaCl-treated mutant is extremely sensitive to HO. In this study, the ultrastructural changes occurring in the mutant and the wild-type cells are analyzed to understand the cellular basis of the above-mentioned protective phenomena. Other data show that a wide variety of osmolytes induce expression in , indicating that is a genuine osmo-inducible gene. These results have important biotechnological implications for the development of novel cyanobacterial biofertilzers and transgenic plants with improved resistance to salinity.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100657PMC
http://dx.doi.org/10.1080/19420889.2016.1216738DOI Listing

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