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A Systematic Review and Meta-Analysis of Stem Cell Therapies for Pain in Diabetic Neuropathy, Osteoarthritis, and Spinal Cord Injuries.
Curr Pain Headache Rep
January 2025
Departments of Anesthesiology and Pharmacology, Toxicology, and Neurosciences, Louisiana State University Health Sciences Center Shreveport, Shreveport, LA, 71103, USA.
Purpose Of Review: The use of stem cell therapy is a rapidly evolving and progressing frontier of science that has been used to treat illnesses such as malignancies, immunodeficiencies, and metabolic syndromes. This review aims to give an overview of the use of stem cell therapy in the treatment of pain caused by diabetic neuropathy, osteoarthritis, and other spinal cord pathologies.
Recent Findings: Pain is defined as a generalized or localized feeling of distress related to a physical or emotional stimulus and can be caused by a multitude of pathologies.
Evaluation and Comparison of the Efficacy and Safety of Erbium YAG Laser Along With Normal Saline vs. Its Combination With Stromal Vascular Fraction (SVF) and Platelet-Rich Plasma (PRP) in the Treatment of Striae Distensae: A Double-Blind Randomized Clinical Trial.
J Cosmet Dermatol
January 2025
Department of Dermatology, Rasool Akram Medical Complex Clinical Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Background: There is no definitive solution for the treatment of striae distensae (SD), and effectiveness of each treatment method remains controversial. We aimed to investigate and compare the efficacy of the combination of Erbium YAG (Er:YAG) laser and stromal vascular fraction (SVF), the combination of Er:YAG laser and platelet-rich plasma (PRP) and Er:YAG laser plus saline in the treatment of SD.
Materials And Methods: In 12 participating patients with at least three lesions (36 lesions in total), each lesion was treated with an Er:YAG laser.
Arthritis: Knee and Hip Osteoarthritis.
FP Essent
January 2025
Family medicine residency program at Rutgers University/Robert Wood Johnson University Hospital Somerset, Somerville, NJ.
Knee and hip osteoarthritis (OA) are two of the leading causes of disability globally. Knee OA is characterized by gradual degeneration of articular cartilage, leading to pain, stiffness, and functional limitations. Patients older than 50 years typically present with knee OA, but it can manifest earlier, particularly following traumatic knee injuries.
View Article and Find Full Text PDFAutonomous Anticoagulation on a Biomimetic Al-Based Hierarchical Surface.
ACS Appl Mater Interfaces
January 2025
Key Laboratory of Bionic Engineering Ministry of Education, Jilin University, Changchun 130025, China.
Studies targeting the blood repellency and autonomous anticoagulation of superhydrophobic (SH) surfaces are potentially valuable for their application in blood contact. The anticoagulation abilities and potential mechanisms of different SH surfaces urgently need to be revealed. In this study, a range of microprotrusion arrays on Al substrates with varying spacings via laser ablation through the utilization of organic adsorption and siloxane coupling reactions were fabricated.
View Article and Find Full Text PDFPlatelet-rich plasma alleviates skin photoaging by activating autophagy and inhibiting inflammasome formation.
Naunyn Schmiedebergs Arch Pharmacol
January 2025
Department of Dermatology, Dongshan Hospital, Guofengyuan Building, Xuezi Avenue, Meijiang District, Meizhou, 514011, Guangdong, China.
Platelet-rich plasma (PRP) holds promising prospects for the treatment of skin photoaging. This study aims to unravel the mechanism underlying PRP's anti-photoaging properties. Partial skin of rats was irradiated with ultraviolet (UV) and injected with PRP, and the skin appearance, pathological state, and aging conditions were determined.
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