Combined optical coherence tomography and hyperspectral imaging using a double-clad fiber coupler.

J Biomed Opt

École Polytechnique Montreal, Department of Engineering Physics, C.P. 6079 Succ. Centre-ville, Montréal, CanadacCastor Optics, 5155 Avenue Decelles 1251, Pavillon J-Armand Bombardier, Montréal, Québec H3T 2B1, Canada.

Published: November 2016

AI Article Synopsis

  • The study presents a method that merges optical coherence tomography (OCT) and hyperspectral imaging (HSI) using a specialized optical fiber coupler.
  • The OCT component captures 3D images of sample structures, while the HSI analyzes the sample's reflectance to provide molecular information.
  • This combined approach can enhance tissue identification in clinical settings, aiding in better diagnosis and surgical procedures.

Article Abstract

This work demonstrates the combination of optical coherence tomography (OCT) and hyperspectral imaging (HSI) using a double-clad optical fiber coupler. The single-mode core of the fiber is used for OCT imaging, while the inner cladding of the double-clad fiber provides an efficient way to capture the reflectance spectrum of the sample. The combination of both methods enables three-dimensional acquisition of the sample morphology with OCT, enhanced with complementary molecular information contained in the hyperspectral image. The HSI data can be used to highlight the presence of specific molecules with characteristic absorption peaks or to produce true color images overlaid on the OCT volume for improved tissue identification by the clinician. Such a system could be implemented in a number of clinical endoscopic applications and could improve the current practice in tissue characterization, diagnosis, and surgical guidance.

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Source
http://dx.doi.org/10.1117/1.JBO.21.11.116008DOI Listing

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