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Self-administered versus clinician-performed BinaxNOW COVID rapid test: a comparison of accuracy.
Microbiol Spectr
March 2024
Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
We conducted a single-center study at a free community testing site in Baltimore City to assess the accuracy of self-performed rapid antigen tests (RATs) for COVID-19. Self-administered BinaxNOW RATs were compared with clinician-performed RATs and against a reference lab molecular testing as the gold standard. Of the 953 participants, 14.
View Article and Find Full Text PDFComparability of Elezanumab Safety, Tolerability, and Pharmacokinetics in Healthy Japanese, Chinese, and White Participants.
Clin Pharmacol Drug Dev
February 2024
Clinical Pharmacology, AbbVie Inc, North Chicago, IL, USA.
Elezanumab is a fully human monoclonal antibody, which is directed against repulsive guidance molecule A. The safety, tolerability, pharmacokinetics (PK), and immunogenicity of elezanumab were assessed in 2 Phase 1 clinical studies. The objective of this study was to assess the PK, safety, tolerability, and immunogenicity following intravenous infusion of elezanumab in healthy adult Japanese, Han Chinese, and Caucasian participants as well as Western participants from the single-ascending-dose study.
View Article and Find Full Text PDFFeasibility of and Experience With Free State-Funded Telehealth-Based Patient Self-referral for COVID-19 Monoclonal Antibody Therapy.
Disaster Med Public Health Prep
September 2023
Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Background: Monoclonal antibody (mAb) treatment for coronavirus disease 2019 (COVID-19) has been underutilized due to logistical challenges, lack of access, and variable treatment awareness among patients and health-care professionals. The use of telehealth during the pandemic provides an opportunity to increase access to COVID-19 care.
Methods: This is a single-center descriptive study of telehealth-based patient self-referral for mAb therapy between March 1, 2021, and October 31, 2021, at Baltimore Convention Center Field Hospital (BCCFH).
Accuracy of Expired BinaxNOW Rapid Antigen Tests.
Microbiol Spectr
August 2023
Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
The widespread existence of expired antigen testing kits in households and potential coronavirus outbreaks necessitates evaluating the reliability of these expired kits. Our study examined BinaxNOW COVID-19 rapid antigen tests 27 months postmanufacture and 5 months past their FDA extended expiration dates, using SARS-CoV-2 variant XBB.1.
View Article and Find Full Text PDFHealth care policy that relies on poor measurement is ineffective: Lessons from the hospital readmissions reduction program.
Health Serv Res
June 2023
Division of Geriatrics and Gerontology, Department of Medicine, Center for Health Disparities Research, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
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