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Mycopathologia
January 2025
Peking University People's Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, People's Republic of China.
Background: Interdigital tinea pedis is a common type of tinea pedis that occurs between toes and is easy to recur. Recently, the skin microbiome analysis of interdigital tinea pedis showed changes in bacterial microbiome in addition to fungal infection.
Objectives: To investigate the efficacy and safety of clioquinol 3% cream in treating interdigital tinea pedis as well as characterize changes in the skin microbiome during treatment.
Sensors (Basel)
December 2024
Department of Physics, Yonsei University, Seoul 03722, Republic of Korea.
The rapid and reliable detection of pathogenic bacteria remains a significant challenge in clinical microbiology. Consequently, the demand for simple and rapid techniques, such as antimicrobial peptide (AMP)-based sensors, has recently increased as an alternative to traditional methods. Melittin, a broad-spectrum AMP, rapidly associates with the cell membranes of various gram-positive and gram-negative bacteria.
View Article and Find Full Text PDFACS Appl Mater Interfaces
December 2024
Department of Electrical Engineering, Indian Institute of Technology, Hyderabad, Telangana 502285, India.
This work presents a facile, ultrasensitive, and selective chemiresistive biosensor assisted by an adaptive signal extraction algorithm (ASEA) for detecting vimentin, a potential biomarker for ovarian cancer detection. The low-cost device, fabricated on a PCB substrate through sacrificial copper etching, features a 3D-IDE design with interwoven comb-like structures mimicking the natural symmetry of a droplet. An unequal count of positive and negative concentric circle fingers ensures a uniform, higher electric field over the sensor's surface, as verified by COMSOL Multiphysics 3D simulation.
View Article and Find Full Text PDFLangmuir
December 2024
Center for Algorithmic and Robotized Synthesis, Institute for Basic Science (IBS), Ulsan 44919, Republic of Korea.
Extracellular vesicles (EVs) are small lipid vesicles shed by cells, carrying proteins, nucleic acids, and other molecular fingerprints. EVs have emerged as crucial mediators of cell-to-cell communication and hold great promise as biomarkers for liquid biopsies, enabling disease screening, diagnosis, prognosis, and monitoring. However, conventional EV separation methods are hampered by the presence of lipoproteins (LPs) in plasma samples, which have comparable characteristics and significantly outnumber EVs.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
State Key Laboratory of Marine Food Processing and Safety Control, Dalian Polytechnic University, Dalian, Liaoning, 116034, China.
Bacterial infection is a crucial factor resulting in public health issues worldwide, often triggering epidemics and even fatalities. The accurate, rapid, and convenient detection of viable bacteria is an effective method for reducing infections and illness outbreaks. Here, an unsupervised learning-assisted and surface acoustic wave-interdigital transducer-driven nano-lens holography biosensing platform is developed for the ultrasensitive and amplification-free detection of viable bacteria.
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