Background: Clinical trials (CT) represent an important treatment option for cancer patients. Unfortunately, patients face challenges to enrolling in CTs, such as logistical barriers, poor CT understanding and complex clinical regimens. Patient navigation is a strategy that may help to improve the delivery of CT education and support services. We examined the feasibility and initial effect of one navigation strategy, use of lay navigators.
Methods: A lay CT navigation intervention was evaluated in a prospective cohort study among 40 lung and esophageal cancer patients. The intervention was delivered by a trained lay navigator who viewed a 17-minute CT educational video with each patient, assessed and answered their questions about CT participation and addressed reported barriers to care and trial participation.
Results: During this 12-month pilot project, 85% (95% CI: 72%-93%) of patients eligible for a therapeutic CT consented to participate in the CT navigation intervention. Among navigated patients, CT understanding improved between pre- and post-test (means 3.54 and 4.40, respectively; p-value 0.004), and 95% (95% CI: 82%-98%) of navigated patients consented to participate in a CT. Navigated patients reported being satisfied with patient navigation services and CT participation.
Conclusions: In this formative single-arm pilot project, initial evidence was found for the potential effect of a lay navigation intervention on CT understanding and enrollment. A randomized controlled trial is needed to examine the efficacy of the intervention for improving CT education and enrollment.
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http://dx.doi.org/10.1016/j.conctc.2016.04.005 | DOI Listing |
Sci Total Environ
January 2025
Advanced Manufacturing School, Nanchang University, Nanchang 330031, China.
Dust deposition on the surface of photovoltaic (PV) modules will reduce power generation efficiency and field service life. Existing research has deficiencies in terms of the adaptation of influencing factors and deposition types, deposition mechanism, numerical model of dust deposition process and time scale of dust deposition problem research. To address these deficiencies, first, this study applies the association diagram method to systematically identify the relevant factors of dust deposition, establishes an adaptive relationship between influencing factors and dust deposition types, improves the existing deposition mechanism, and proposes dust deposition criteria.
View Article and Find Full Text PDFFront Genet
December 2024
Department of Economics, Faculty of Social Sciences, Brock University, St. Catharines, ON, Canada.
Although lab-coat genomics scientists are highly skilled and involved in pioneering work, few studies have examined their perceptions on what they do, and how they relate with others in interdisciplinary work. Recognizing that gap, we were curious to talk with scientists about their current work and positionalities related to the use of genomics for bioremediation. Using unstructured open-ended interviews and thematic analysis, we interviewed researchers with diverse genomics-related expertise.
View Article and Find Full Text PDFWest J Nurs Res
December 2024
School of Health Sciences, University of South Dakota, Vermillion, SD, USA.
Background: Rural communities, like other places in the United States, face a growing need for palliative care. Community health workers (CHWs) are one potential way to expand the ability to provide palliative care. This scoping review explores what is known about CHWs involved in palliative care teams in the United States.
View Article and Find Full Text PDFJ Adv Nurs
December 2024
Hematology & Oncology Department, Children's Hospital of Fudan University, Shanghai, China.
Aims: To explore the practical experiences and perceived needs of healthcare professionals in fostering resilience among bereaved parents.
Design: A qualitative descriptive study was conducted.
Methods: Twenty-seven healthcare professionals were recruited from the Paediatric Palliative Care Special Group of the Paediatrics Society of the Chinese Medical Association.
Refugee and non-refugee migrant youths may carry a double burden of past adversities and post-migration stress while trying to continue schooling and adapt to their new social and cultural environment. Executive functioning skills are central to learning and navigating in the new context. Knowledge of how young migrants' executive functioning is associated with stressful factors and positive or potentially protective factors, could contribute to understanding and possibly finding ways to support these young learners.
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