Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/TP.0000000000001560 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Novel Dynamic Organ Storage System Enhances Liver Graft Function in a Porcine Donation After Circulatory Death Model.
ASAIO J
December 2024
Department of Cardiac Surgery, Vanderbilt University Medical Center, Nashville, Tennessee.
Donation after circulatory death (DCD) livers face increased risks of critical complications when preserved with static cold storage (SCS). Although machine perfusion (MP) may mitigate these risks, its cost and logistical complexity limit widespread application. We developed the Dynamic Organ Storage System (DOSS), which delivers oxygenated perfusate at 10°C with minimal electrical power requirement and allows real-time effluent sampling in a portable cooler.
View Article and Find Full Text PDFPancreas transplantation with grafts obtained from donation after cardiac death or donation after brain death results in comparable outcomes.
Front Transplant
August 2023
Ajmera Transplant Centre, Toronto General Hospital, Toronto, ON, Canada.
Introduction: Pancreas organ shortages and long recipient waitlist times are critical components that limit recipients from receiving a pancreas transplant. Over the last decade, our center has been using donation after cardiac death (DCD) donors as an adjunct to donation after brain death (DBD) donors to expand the organ pool. The aim of this study was to compare recipient and graft survival between DCD and DBD recipients.
View Article and Find Full Text PDFSimultaneous Pancreas and Kidney Transplantation from Donors after Circulatory Death in Switzerland.
J Clin Med
June 2024
Department of Surgery and Transplantation, University Hospital Zurich, 8091 Zurich, Switzerland.
Simultaneous pancreas and kidney transplantation (SPK) remains the only curative treatment for type I diabetics with end-stage kidney disease. SPK using donors after circulatory death (DCD) is one important measure to expand the organ pool for pancreas transplantation (PT). After initial doubts due to higher complications, DCD SPK is now considered safe and equivalent to donation after brain death in terms of survival and graft function.
View Article and Find Full Text PDFEvaluating Islet Cell Isolation and Transplantation From Donors Following Medical Assistance in Dying.
Transplant Direct
July 2024
Clinical Islet Transplant Program, University of Alberta, Edmonton, AB, Canada.
Background: Limited information is available regarding outcomes of islet cell isolation (ICI) and transplantation (ITx) using medical assistance in dying (MAiD) donors. We aimed to assess the feasibility and outcomes of ICI and ITx in MAiD donors.
Methods: ICI and ITx from MAiD were compared with donation after circulatory death (DCD) type III between 2016 and 2023.
Exploring Preservation Modalities in a Split Human Pancreas Model to Investigate the Effect on the Islet Isolation Outcomes.
Transplant Direct
July 2024
Surgery and Abdominal Transplantation Division, Department of Surgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Article Synopsis
- This study evaluated three pancreas preservation techniques: static cold storage, hypothermic machine perfusion (HMP), and oxygenated HMP, focusing on their effects on islet transplantation.
- The methodology involved using discarded human pancreas organs from both brain death and circulatory death donors, comparing outcomes in islet yield, function, histology, and other factors.
- Results indicated no significant differences in islet functionality or histology among the preservation methods, although DCD organs showed higher islet purity in the HMP group, highlighting the need for more research in this area.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!