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| http://dx.doi.org/10.1038/npp.2016.137 | DOI Listing |
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Liquid biopsy enables real-time monitoring of tumor development and response to therapy through the analysis of CTCs and ctDNA. NALCN is a sodium leak channel that is frequently involved in tumor evolution and immunity and acts as a tumor suppressor. Deletion of NALCN has been shown to increase cancer metastasis and the number of CTCs in peripheral blood.
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Lab of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, 15771 Athens, Greece.
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: Non-Small Cell Lung Cancer (NSCLC) remains a challenging disease to manage with effectiveness. Early detection and precise monitoring are crucial for improving patient outcomes. Circulating tumor DNA (ctDNA) offers a non-invasive cancer detection and monitoring method.
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Laboratory of Analytical Chemistry, Department of Chemistry, National and Kapodistrian University of Athens, Zografou, 15771 Athens, Greece. Electronic address:
Molecular-based assays are the most commonly used methods for the detection and quantification of viruses in wastewater. The variety of inhibitory substances present in the complex matrix of wastewater hinders downstream analysis and often leads to false negative results and underestimation of viral load. The development of robust and inhibitor-tolerant detection methods is necessary in the context of wastewater-based epidemiology, a valuable tool that has gained further importance since the emergence of the Covid-19 pandemic.
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