Immune modules shared by innate lymphoid cells and T cells.

J Allergy Clin Immunol

Department of Pathology & Immunology, Washington University School of Medicine, St Louis, Mo. Electronic address:

Published: November 2016

In recent years, innate lymphoid cells (ILCs) have emerged as innate correlates to T cells. The similarities between ILCs and T cells indicate that lymphocytes of fundamentally distinct lineages can share core "immune modules" that encompass transcriptional circuitry and effector functions while using nonredundant complementary mechanisms of pattern recognition to enact these functions. We review modules currently recognized to be shared between ILCs and T cells.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111630PMC
http://dx.doi.org/10.1016/j.jaci.2016.09.006DOI Listing

Publication Analysis

Top Keywords

innate lymphoid
8
lymphoid cells
8
ilcs t cells
8
immune modules
4
modules shared
4
shared innate
4
t cells
4
cells t cells
4
t cells years
4
years innate
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!