A Fluorescein-Based Colorimetric and Fluorescent Probe for Hydrazine and its Bioimaging in Live Cells.

J Fluoresc

Phosphorus Chemical Engineering Research Center of Henan Province, the College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, 450052, China.

Published: January 2017

A turn-on fluorescent probe (FN) for detection of hydrazine has been developed. Probe FN exhibited high selectivity and excellent sensitivity towards hydrazine with a detection limit as low as 4.6 × 10 M. Probe FN selectively reacts with hydrazine (NH) in a physiological environment, leading to an off-on fluorescence response along with the color change from colorless to yellow, allowing colorimetric detection of hydrazine by the naked eye. Furthermore, probe FN was successfully applied for visualizing hydrazine in living cells.

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http://dx.doi.org/10.1007/s10895-016-1961-6DOI Listing

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