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Exhaled breath metabolites reveal postmenopausal gut-bone cross-talk and non-invasive markers for osteoporosis.
Commun Med (Lond)
December 2024
Rostock Medical Breath Research Analytics and Technologies (ROMBAT), Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, Rostock University Medical Center, Rostock, Germany.
Background: Menopause driven decline in estrogen exposes women to risk of osteoporosis. Detection of early onset and silent progression are keys to prevent fractures and associated burdens.
Methods: In a discovery cohort of 120 postmenopausal women, we combined repeated quantitative pulse-echo ultrasonography of bone, assessment of grip strength and serum bone markers with mass-spectrometric analysis of exhaled metabolites to find breath volatile markers and quantitative cutoff levels for osteoporosis.
Climate displaces deposition as dominant driver of dissolved organic carbon concentrations in historically acidified lakes.
Biogeochemistry
December 2024
Department of Natural Resources and the Environment, University of New Hampshire, 56 College Road, Durham, NH USA.
Unlabelled: Climate and atmospheric deposition interact with watershed properties to drive dissolved organic carbon (DOC) concentrations in lakes. Because drivers of DOC concentration are inter-related and interact, it is challenging to assign a single dominant driver to changes in lake DOC concentration across spatiotemporal scales. Leveraging forty years of data across sixteen lakes, we used structural equation modeling to show that the impact of climate, as moderated by watershed characteristics, has become more dominant in recent decades, superseding the influence of sulfate deposition that was observed in the 1980s.
View Article and Find Full Text PDFDifferences in Gut Microbes Across Age and Sex Linked to Metabolism and Microbial Stability in a Hibernating Mammal.
Ecol Evol
November 2024
Department of Ecology and Evolutionary Biology UCLA Los Angeles California USA.
The gut microbiome has a well-documented relationship with host fitness, physiology, and behavior. However, most of what is known comes from captive animals where diets and environments are more homogeneous or controlled. Studies in wild populations that experience dynamic environments and have natural life history variation are less common but are key to understanding the drivers of variation in the gut microbiome.
View Article and Find Full Text PDFRemoval efficiencies for 52 pesticides and pharmaceuticals from wastewater effluent by coupling solar heterogeneous photo-oxidation with TiO and infiltration in saturated soil column.
Sci Total Environ
December 2024
Laboratoire PROcédés, Matériaux et Energie Solaire, PROMES-CNRS UPR8521, Rambla de la Thermodynamique, Tecnosud, 66100 Perpignan, France.
Water resource management has become a hot button issue in recent decades. Countries facing water shortages as a result to climate change must adapt their water supply. The reuse of wastewater treatment plant effluents is becoming increasingly common around the world.
View Article and Find Full Text PDFDegradation Effects in LiTiO-Based Cells─Learning from Electrode Potential Profiles.
ACS Appl Mater Interfaces
November 2024
MEET Battery Research Center, University of Münster, Corrensstr. 46, 48149 Münster, Germany.
LiTiO (LTO) is a promising negative electrode active material for high-power applications of lithium-ion batteries due to its structural and dimensional stability, high safety properties, and rate capability. However, there are still challenges regarding the cyclic aging behavior of LTO-based cells, especially when it comes to the origin of gas evolution that needs to be resolved in order to enable an optimized cell design and prolonged cycle life. Using a three-electrode setup provides operando insights into the cyclic aging behavior of LiNiCoMnO (NCM111)||LTO cells.
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