Enamel alterations, such as amelogenesis imperfecta, can compromise the harmony of the smile and the patient's self-esteem and may cause tooth sensitivity. A simple and effective treatment approach uses the natural stratification of composite resins to mask deficient enamel formation and mimic the natural appearance of the substrate. The operative steps and principles for restorative success are described in this case report with 36-month follow-up.

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Amelogenesis imperfecta refers to a group of hereditary diseases that affect dental enamel, often leading to a wide range of clinical manifestations and aesthetic concerns. This case report describes a female patient diagnosed with amelogenesis imperfecta associated with a skeletal open bite. The treatment approach was multidisciplinary.

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Introduction: Childhood early oral ageing syndrome (CEOAS) is a condition involving oral abnormalities resulting from systemic diseases of different origins that are related to the current lifestyle of the paediatric population. Enamel defects associated with intrinsic and extrinsic factors promote the early loss of tooth structure at an accelerated pace, with negative impacts on function, aesthetics and quality of life. The aim of the study is to identify the prevalence of early tooth wear in childhood and its severity using the CEOAS index, which is a tool for the diagnosis of the condition and for epidemiological surveys, involving the investigation of abnormalities of the oral cavity in the paediatric population and possible factors associated with the severity of the condition.

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Molecular Study of FAM20A Gene and Biochemical Analysis for Amelogenesis Imperfecta Patients.

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December 2024

DEPARTMENT OF ORAL DIAGNOSIS, COLLEGE OF DENTISTRY, COLLEGE OF DENTISTRY, UNIVERSITY OF BAGHDAD, BAGHDAD, IRAQ.

Objective: Aim: This study aimed to diagnose Amelogenesis Imperfecta patients if have an isolated type or are related to a syndrome such as enamel renal syndrome.

Patients And Methods: Materials and Methods: This case-control study included (60 patients and 20 controls). DNA extraction from the blood sample then used the Conventional PCR reaction and Agarose Gel Electrophoresis.

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Amelogenesis imperfecta is a collection of genetic disorders that impair the structure of dental enamel. The condition presents in a variety of ways, affecting enamel development, mineralization, and maturation. Amelogenesis imperfecta can follow various inheritance patterns, including autosomal dominant, autosomal recessive, sex-linked, and sporadic.

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Enamel Renal Syndrome: A Case Report.

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Oral and Maxillofacial Pathology, Microbiology and Forensic Odontology, Goa Dental College and Hospital, Panjim, IND.

Article Synopsis
  • - Amelogenesis imperfecta is a genetic disorder that affects the enamel of teeth, which can lead to problems in both baby and adult teeth, sometimes linked with other health issues.
  • - A rare condition called enamel renal syndrome occurs when amelogenesis imperfecta is found alongside kidney stones, which complicates diagnosis due to unclear criteria.
  • - The case of a 12-year-old boy with tooth discoloration and kidney stones highlights the importance of thorough medical evaluations to avoid serious complications from these conditions.
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