Human pathogenic fungi are highly adaptable to a changing environment. The ability to adjust to low oxygen conditions is crucial for colonization and infection of the host. Recently, the impact of mammalian hypoxia-inducible factor-1α (HIF-1α) on fungal immunity has emerged. In this review, the role of hypoxia and HIF-1α in fungal infections is discussed regarding the innate immune response.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6863052 | PMC |
| http://dx.doi.org/10.1016/j.micinf.2016.10.008 | DOI Listing |
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