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http://dx.doi.org/10.1056/NEJMp1608301 | DOI Listing |
Chem Commun (Camb)
September 2024
Department of Chemistry, Indian Institute of Technology Patna, Bihar, 801106, India.
The existence of life beyond Earth has long captivated humanity, and the study of extremophiles-organisms surviving and thriving in extreme environments-provides crucial insights into this possibility. Extremophiles overcome severe challenges such as enzyme inactivity, protein denaturation, and damage of the cell membrane by adopting several strategies. This feature article focuses on the molecular strategies extremophiles use to maintain the cell membrane's structure and fluidity under external stress.
View Article and Find Full Text PDFJ Cosmet Dermatol
June 2024
Dermatology Unit "Daniele Innocenzi", "A. Fiorini" Hospital, Terracina, Italy.
Environ Manage
January 2024
Faculty of Health, Charles Darwin University, Casuarina, NT, Australia.
The uncertainty of climate change is a significant challenge prompting Australian farmers to create different thinking and different management systems that ensure sustained farm business viability and continuity, particularly in extreme environments. The purpose of this study was to explore the conditions and adaptive processes for managing farm resilience and cyclic adaptation pathways, in response to climate change. A positive deviance sample of farmers was interviewed, and data was collected from a cohort of twenty-two climate change innovators across Eastern Australia.
View Article and Find Full Text PDFRural Remote Health
January 2023
Unidade Local de Saúde da Guarda, Guarda, Portugal
Introduction: The LEAN methodology is an integration of methods and tools developed in the 90s in the industrial sector. It aims to reduce waste (things that don't add value to the final product), add worth and work towards continuous quality improvement.
Methods: LEAN tools to improve the clinical practice of a health center include:5S methodology: helps organize, clean, develop and maintain a productive work environment;'Spaghetti' diagram: displays the movement and distance that a given element has to travel throughout the entire process; andTime and motion studies: measure the various times associated with the process and the associated motion.
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