Zemková, E, Cepková, A, Uvaček, M, and Šooš, L. A novel method for assessing muscle power during the standing cable wood chop exercise. J Strength Cond Res 31(8): 2246-2254, 2017-The study estimates the repeatability and sensitivity of a novel method for assessing (a) the maximal power during the standing cable wood chop exercise with different weights and (b) the endurance of the core muscles. A group of 23 fit men performed (a) maximal effort single repetitions of the standing cable wood chop exercise with weights increasing stepwise up to 1 repetition maximum (1RM) and (b) a set of 20 repetitions at a previously established weight at which maximal power was achieved. Results showed that mean power during the standing cable wood chop exercise is a reliable parameter, with intraclass correlation coefficient values above 0.90 for all weights tested. It was also shown to be a sensitive parameter able to discriminate within-group differences in the maximal power and endurance of core muscles. Substantial individual differences were found in mean power, especially at higher weights, and in the maximal power achieved at about 75% of 1RM (462.2 ± 57.4 W, n = 11), 67% of 1RM (327.2 ± 49.7 W, n = 7), and 83% of 1RM (524.0 ± 63.2 W, n = 5). At these weights, there were also significant differences between the initial and the final repetitions of the wood chop exercise (13.9%, p = 0.025; 10.2%, p = 0.036; and 13.8%, p = 0.028, respectively). These findings indicate that evaluation of the maximal power and endurance of the core muscles during the standing cable wood chop exercise on a weight stack machine is a reliable method and sensitive to differences among physically active individuals.
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http://dx.doi.org/10.1519/JSC.0000000000001692 | DOI Listing |
Childs Nerv Syst
January 2025
Division of Neurosurgery, Department of Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Purpose: We sought to evaluate the incidence, natural history, and management of cystic spinal lesions following myelomeningocele/myeloschisis closure.
Methods: We performed a single-center retrospective review of all patients who underwent myelomeningocele/myeloschisis closure from 2013 to 2018 with follow-up to 5 years old.
Results: We analyzed 100 fetal repairs and 81 postnatal closures from 305 total surgeries.
Pediatr Cardiol
December 2024
Division of Pediatric General, Thoracic, and Fetal Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Fetoscopic endoluminal tracheal occlusion (FETO) induces lung growth and may improve survival in congenital diaphragmatic hernia (CDH) but the effect on post-natal right (RV) and left (LV) ventricular size and cardiac function is unknown. Quantitative measures of heart size and function including tricuspid annular plane systolic excursion Z-score (TAPSEZ), RV fractional area change (RVFAC), RV global longitudinal and free wall strain (RVGLS, RVFWS), RV/LV ratio, LV eccentricity index (LVEI), and LV M-mode diastolic and systolic Z-scores (LVIDDZ, LVIDSZ) were compared between FETO and control patients on first post-natal echocardiogram, prior to and post CDH repair, and on last available echocardiogram using non-parametric Wilcoxon rank-sum test in a single-center, retrospective cohort study. Linear regression models evaluated change over time, adjusting for clustering and interaction of echocardiogram parameters with time.
View Article and Find Full Text PDFVet Sci
November 2024
Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada.
The majority of canine lymphoma patients treated with the standard of care, the CHOP chemotherapy protocol, initially achieve remission but eventually relapse with a multi-drug-resistant phenotype. This study assesses gene expression profiles of canine lymphoma tumor cell populations using RNA-Seq data from 15 matched patient samples taken prior to treatment and again six weeks into treatment with CHOP. Two distinct clusters were present in the t-SNE dimensionality reduction of the gene expression profiles.
View Article and Find Full Text PDFNat Cancer
November 2024
Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Refractoriness to initial chemotherapy and relapse after remission are the main obstacles to curing T cell acute lymphoblastic leukemia (T-ALL). While tumor heterogeneity has been implicated in treatment failure, the cellular and genetic factors contributing to resistance and relapse remain unknown. Here we linked tumor subpopulations with clinical outcome, created an atlas of healthy pediatric hematopoiesis and applied single-cell multiomic analysis to a diverse cohort of 40 T-ALL cases.
View Article and Find Full Text PDFJ Perinatol
November 2024
Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
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