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Investigation Myocardial Perfusion Scan Parameters and Walls Motion in Patients undergoing Cardiac Surgery.
J Biomed Phys Eng
December 2024
Department of Medical Physics and Engineering, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Background: Coronary heart disease the most prevalent form of cardiovascular disease, results from the blockage of blood flow through arteries. The Myocardial Perfusion Scan (MPS) is considered a non-invasive method to assess the heart condition and provides valuable information, such as End Diastolic Volume (EDV), End Systolic Volume (ESV), Ejection Fraction (EF), Lung to Heart Ratio (LHR), and Transient Ischemic Dilatation (TID).
Objective: This study aimed to investigate changes in gated heart scan parameters to diagnose patients, who are candidates for heart surgery.
Dilatory responsiveness of the internal carotid artery to shear stimulus is constant under different levels of transient hypercapnia.
J Appl Physiol (1985)
December 2024
School of Health Science, Sapporo Medical University, Sapporo, Japan.
Peripheral endothelial function, which accounts for the variability in shear stimulus, can be assessed using shear-mediated dilation normalized to the increased shear stimulus. Similarly, shear-mediated dilation of the internal carotid artery (ICA), an index of cerebrovascular endothelial function, should be normalized to increased shear stimulus. However, this approach has not yet been validated.
View Article and Find Full Text PDFDilated cardiomyopathy variant R14del increases phospholamban pentamer stability, blunting dynamic regulation of calcium.
J Biol Chem
December 2024
Department of Cell and Molecular Physiology, Loyola University Chicago, Maywood, IL, USA. Electronic address:
The sarco(endo)plasmic reticulum Ca ATPase (SERCA) is a membrane transporter that creates and maintains intracellular Ca stores. In the heart, SERCA is regulated by an inhibitory interaction with the monomeric form of the transmembrane micropeptide phospholamban (PLB). PLB also forms avid homo-pentamers, and dynamic exchange of PLB between pentamers and SERCA is an important determinant of cardiac responsiveness to exercise.
View Article and Find Full Text PDFDuplicate gallbladders misdiagnosed as residual cholecystitis: A case report and review of the literature.
Medicine (Baltimore)
December 2024
Department of Hepatobiliary Surgery, Yangxin People's Hospital, Yangxin, China.
Rationale: Duplication of gallbladder is a rare anomaly in humans, as it is very rare for a duplication of gallbladder to be missed during the first cholecystectomy and thus require a second cholecystectomy.
Patient Concerns: A 42-year-old man came to our hospital with paroxysmal right upper abdominal pain for 10 days. In addition to the pain, he also had transient jaundice.
Much More Than a Stroke: Emery-Dreifuss Muscular Dystrophy Type 2 Revealed by Ischemic Stroke.
Cureus
November 2024
Stroke Unit, Centro Hospitalar Tondela-Viseu, Viseu, PRT.
Emery-Dreifuss muscular dystrophy type 2 (EDMD2) is a rare autosomal dominant neuromuscular disorder caused by LMNA gene mutations and characterized by progressive skeletal muscle weakness and significant cardiac involvement. We report the case of a 45-year-old woman who presented with sudden-onset, left-sided hemiparesis and dysarthria. Initial imaging was unremarkable, and symptoms transiently improved, suggesting a transient ischemic attack.
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