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| http://dx.doi.org/10.1038/tp.2016.187 | DOI Listing |
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Do adolescents with different types and degrees of idiopathic scoliosis curves differ in postural control compared to their healthy peers? a cross-sectional study.
BMC Musculoskelet Disord
December 2024
School of Health and Social Care, Department of Allied Health Professions, University of Teesside, Middlesbrough, UK.
Background: Numerous scoliosis research studies have investigated postural control changes in adolescents with idiopathic scoliosis and compared them to healthy controls. However, the results have been controversial. Therefore, the present study aimed to compare whether postural control in adolescent idiopathic scoliosis (AIS) patients is different from their age-matched healthy counterparts.
View Article and Find Full Text PDFThe Potential Protective Role of Ascorbic Acid Against Testicular Toxicity Induced by Fluoxetine in Male Wistar Rats.
J Exp Pharmacol
November 2024
Department of Human Anatomy, Kampala International University, Bushenyi, Uganda.
Article Synopsis
- Fluoxetine (FLX) is a common antidepressant that can negatively affect male fertility by increasing Reactive Oxygen Species (ROS), prompting this study on the protective effects of Vitamin C.
- The study involved treating male Wistar rats with fluoxetine and various doses of Vitamin C over 60 days, measuring their testicular weight, sperm parameters, and oxidative stress markers.
- Results showed that higher doses of Vitamin C improved fertility outcomes, increased antioxidant enzyme levels, and protected testicular structure from FLX damage, indicating its potential as a treatment for drug-induced fertility issues.
Adequacy of treatment in outpatients with obsessive-compulsive disorder.
Compr Psychiatry
January 2025
Department of Psychiatry, Amsterdam UMC, Amsterdam, The Netherlands; Amsterdam Neuroscience Research Institute, Amsterdam, The Netherlands; Arkin Institute for Mental Health, Amsterdam, The Netherlands.
Objective: To examine whether patients with obsessive-compulsive disorder (OCD) are adequately treated with pharmacotherapy before referral to a specialized center for OCD.
Methods: We performed a retrospective chart review of patients with OCD who were seen for intake at an academic outpatient center in The Netherlands between 2016 and 2023. We collected data on age, gender, illness severity using the Yale-Brown Obsessive-Compulsive Scale, duration of illness, comorbidity and past pharmacotherapy and psychotherapy.
Low-value interventions to deimplement: A secondary analysis of a systematic review of low back pain clinical practice guidelines.
PM R
October 2024
Penn State Health Milton S. Hershey Medical Center, Physical Medicine & Rehabilitation, Hershey, Pennsylvania, USA.
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- The study aimed to review existing clinical practice guidelines (CPGs) for low back pain (LBP) to identify recommendations that could be classified as low-value and suggested for deimplementation.
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Exploring genetic causal relationship between antidepressants use and congenital malformations.
Reprod Toxicol
December 2024
Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, China; International Genome Center, Jiangsu University, Zhenjiang, China. Electronic address:
Article Synopsis
- * The findings suggest a possible link between antidepressant use and specific congenital malformations, particularly digestive and respiratory system issues related to SSRIs, but no significant associations were found for citalopram, paroxetine, or sertraline.
- * The authors conclude that while there is some evidence of a causal relationship between certain antidepressants and congenital malformations, more research is necessary to verify these results and understand the biological mechanisms involved.
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