Introduction: This study aims to determine the prevalence of neonatal surgical emergencies and their epidemiology.
Methods: This retrospective cohort study reports 30 cases whose data were collected in the Department of Surgery at the Bukavu Provincial General Reference Hospital over a period of 3 years, from January 2010 to December 2013.
Results: Neonatal surgical emergencies account for 1.31% of surgical pathologies in general. The most frequent age of patients during medical consultation was less than 8 days. Male prevalence was noted with sex-ratio 3/2. The most frequent pathologies were gastrointestinal tract emergencies (43.3%) followed by neurological emergencies (40%). 80% of newborns underwent surgery. Mortality rate was 43.3%.
Conclusion: Neonatal surgical pathologies occur in our midst. Clinicians should be on alert and implement prenatal diagnostic programs and proper neonatal care management in order to save the lives of these children.
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http://dx.doi.org/10.11604/pamj.2016.24.219.8495 | DOI Listing |
PLoS One
January 2025
Department of Nursing, College of Health Sciences, Injibara University, Injibara, Ethiopia.
Objective: The objective of this systematic review and meta-analysis is to assess and synthesize the global evidence on the level of nurses' knowledge and its determinants regarding the prevention of surgical site infections.
Methods: This systematic review and meta-analysis were conducted following strict methodological guidelines to ensure accuracy and reliability. Adhering to the 2020 PRISMA checklist, a systematic review and meta-analysis sought to establish the pooled proportion of nurse's knowledge and its determinants regarding surgical site infection prevention globally.
Drug Deliv Transl Res
January 2025
Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, 110062, India.
The global prevalence of Parkinson's Disease (PD) is on the rise, driven by an ageing population and ongoing environmental conditions. To gain a better understanding of PD pathogenesis, it is essential to consider its relationship with the ageing process, as ageing stands out as the most significant risk factor for this neurodegenerative condition. PD risk factors encompass genetic predisposition, exposure to environmental toxins, and lifestyle influences, collectively increasing the chance of PD development.
View Article and Find Full Text PDFTransl Vis Sci Technol
January 2025
STZ eyetrial at the Centre for Ophthalmology, Tuebingen, Germany.
Purpose: Reports of gene therapy-associated retinal atrophies and inflammation have highlighted the importance of preclinical safety assessments of adeno-associated virus (AAV) vector systems. We evaluated in nonhuman primates (NHPs) the ocular safety and toxicology of a novel AAV gene therapy targeting retinitis pigmentosa caused by mutations in PDE6A, which has since been used in a phase I/II clinical trial (NCT04611503).
Methods: A total of 34 healthy cynomolgus animals (Macaca fascicularis) were treated with subretinal injections of rAAV.
R I Med J (2013)
February 2025
Division of Trauma and Surgical Critical Care, The Warren Alpert Medical School of Brown University, Rhode Island Hospital, Providence, Rhode Island.
Background: Orthopedic trauma patients are at high risk for venous thromboembolic (VTE) complications. Despite this, VTE prophylaxis is often held peri-operatively out of concern for increased bleeding and associated complications. This review's purpose is to examine guidelines and studies on withholding prophylactic anticoagulation peri-operatively.
View Article and Find Full Text PDFInt J Gynecol Cancer
January 2025
The University of Texas MD Anderson Cancer Center, Department of Gynecologic Oncology and Reproductive Medicine, Houston, TX, USA.
Objective: Hyperglycemia, or glucose values >180 mg/dL, is associated with adverse post-operative outcomes. Our objective was to determine the impact of improving peri-operative glycemic control and evaluate infectious complications among patients with type 2 diabetes mellitus undergoing open gynecologic surgery.
Methods: A multidisciplinary team standardized pre-operative screening, referral algorithms, and intra-operative and post-operative hyperglycemia management (Surgical Universal euGlycemic Attainment during Recovery initiative).
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