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Subcutaneous Sweet's Syndrome Presenting With a Single Cutaneous Lesion on the Thigh.
Cureus
August 2024
Department of Dermatology, JR Sapporo Hospital, Sapporo, JPN.
Article Synopsis
- * Subcutaneous Sweet's syndrome (SSS) is a rare variant presenting as tender nodules resembling EN and can complicate diagnosis due to similar symptoms like fever and elevated inflammatory markers.
- * In a specific case study, a patient had a painful thigh lesion with distinctive histopathological features that indicated SSS rather than EN despite the similarities between the two conditions.
A Rare Case of Chickenpox Infection Complicated by Hip Septic Arthritis.
Cureus
September 2023
Department of Internal Medicine, Al-Ahli Hospital, Hebron, PSE.
Chickenpox represents a viral malady characterized by the emergence of vesicular skin eruptions. This ailment is frequently encountered during childhood and typically manifests a benign course devoid of complications. Among the prevalent complications, secondary bacterial skin infections ranging from superficial impetigo to subcutaneous abscesses are most frequently observed.
View Article and Find Full Text PDFInnate immune response in patients with acute Chikungunya disease.
Med Microbiol Immunol
August 2023
Department of Microbiology and Parasitology, Biosciences Center, Federal University of Rio Grande do Norte. Natal, Rio Grande do Norte, Natal, Rio Grande Do Norte, 59078-970, Brazil.
Chikungunya disease (CHIKD) is an arbovirose that presents with high morbidity, mainly due to arthralgia. Inflammatory mediators including IL-6, IL-1β, GM-CSF and others have been implicated in the pathogenesis of CHIKD, whilst type I interferons can be associated with better outcomes. The role of pattern recognition receptors has been studied incompletely.
View Article and Find Full Text PDFCOVID-19 patients at referral to hospital during the first peak of disease: Common clinical findings including myalgia and fatigue.
Eur J Transl Myol
August 2022
Department of Emergency Medicine, School of Medicine, Health in Disasters and Emergencies Research Center, Kerman University of Medical Sciences, Kerman.
The wide range of manifestations and clinical symptoms of COVID-19 has made it a unique disease. Investigating the epidemiology of different clinical manifestations of this disease in patients referred to medical centers is one of the most effective steps in adopting a suitable diagnostic and treatment approach. These findings also provide a basis for comparing the evolution of the virus and its clinical manifestations over time and at different peaks of the disease.
View Article and Find Full Text PDFA highly attenuated Vesiculovax vaccine rapidly protects nonhuman primates against lethal Marburg virus challenge.
PLoS Negl Trop Dis
May 2022
Department of Viral Vaccine Development, Auro Vaccines, Pearl River, New York, United States of America.
Article Synopsis
- Marburg virus (MARV) poses a serious public health risk due to its high mortality rate and recent outbreaks in West Africa, highlighting the need for effective vaccines as the only licensed vaccine currently is for Ebola (Ervebo).
- A study tested a new vaccine (rVSV-N4CT1-MARV-GP) in cynomolgus monkeys, revealing that 100% survival occurred when vaccinated one week before exposure to the virus, while survival rates dropped significantly with shorter vaccination timelines.
- The findings suggest that Vesiculovax vaccines could be a safer and effective alternative for managing Marburg virus outbreaks, offering a better safety profile compared to existing vaccines like Ervebo, which can cause adverse effects linked to
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